Description

Lipoamido-Peg8-Acid CAS NO 1334172-70-1 is a high-purity, heterobifunctional polyethylene glycol (PEG) derivative featuring a lipoamide group and a terminal carboxylic acid. This compound is engineered to serve as a critical linker and spacer molecule in advanced bioconjugation and nanomaterial synthesis, enabling the precise attachment of bioactive molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing targeted drug delivery systems, diagnostic agents, and functionalized surfaces.

Application

• Bioconjugation Reagent: Used to link peptides, proteins, or antibodies to nanoparticles, dyes, or solid supports via its carboxylic acid group.
• Drug Delivery Systems: Acts as a functionalized PEG spacer in the synthesis of prodrugs and liposomal or polymeric nanoparticle formulations to enhance solubility and circulation time.
• Surface Functionalization: Employed to modify gold nanoparticles, quantum dots, or other nanomaterials with a lipoamide anchor for stable self-assembled monolayers (SAMs).
• Crosslinking Agent: Facilitates the creation of hydrogel networks or polymer-protein conjugates through its reactive end groups.
• Diagnostic Probe Development: Integral in constructing imaging probes where the lipoamide group provides a stable attachment to metal surfaces or cores.
• Biomaterial Modification: Used to impart stealth properties and specific biorecognition capabilities to implantable devices and scaffolds.

Basic Information

Product Name	Lipoamido-Peg8-Acid
CAS No.	1334172-70-1
Molecular Formula	C33H63N3O13S2
Molecular Weight	774.0 g/mol (approx.)
Synonyms	α-Lipoic acid-PEG8-acid; Lipoic Acid-PEG8-COOH; 8-Azido-3,6-dioxaoctanoic acid lipoamide derivative; Heterobifunctional PEG Lipoamide Acid; Thioctic acid-PEG8-carboxylic acid; Lipoamide-PEG8-propionic acid; Lipoic Acid PEG Carboxylic Acid; LA-PEG8-COOH
EINECS	Contact for details

Quality Control

Our Lipoamido-Peg8-Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Molecular Weight Confirmation (MS)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.