Description

Biotin-Teg-NH2 TFA is a high-purity, functionalized biotin derivative designed for advanced bioconjugation and labeling applications. This compound is critical for researchers and manufacturers requiring precise, stable, and site-specific attachment of biotin tags to biomolecules, enabling downstream detection and purification. It is an essential building block for the development of diagnostic assays, targeted drug delivery systems, and proteomics research tools in the pharmaceutical and biotechnology sectors.

Application

• Bioconjugation Reagent: Used for the site-specific biotinylation of peptides, proteins, antibodies, and oligonucleotides.
• Diagnostic Assay Development: A key component in the manufacture of ELISA kits, lateral flow assays, and other immunoassays that utilize streptavidin-biotin technology.
• Affinity Purification Probes: Enables the creation of biotin-tagged ligands for the capture and isolation of target molecules using streptavidin-coated beads or columns.
• Drug Delivery & Targeting: Facilitates the development of biotinylated drug conjugates and nanoparticles for targeted therapeutic applications.
• Proteomics & Biomarker Discovery: Employed in mass spectrometry-based workflows for labeling and enriching low-abundance proteins.
• Cell Surface Labeling: Used to tag cell surface receptors and other membrane proteins for imaging and flow cytometry studies.
• Material Science: Functionalization of surfaces and nanomaterials with biotin for biosensor and diagnostic device fabrication.

Basic Information

Product Name	Biotin-Teg-NH2 TFA
CAS No.	1334172-59-6
Molecular Formula	C23H41N5O7S • C2HF3O2
Molecular Weight	Contact for details
Synonyms	Biotin-PEG3-amine TFA salt; Biotinamido-PEG3-amine TFA; Biotin-PEG3-NH2 TFA; 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(2-(2-(2-aminoethoxy)ethoxy)ethyl)pentanamide trifluoroacetate; Biotin-EG3-NH2 TFA; Biotin-PEG3-NH2 • TFA; Biotin-triethyleneglycol-amine TFA salt; Biotinyl-PEG3-amine TFA
EINECS	Contact for details

Quality Control

Our Biotin-Teg-NH2 TFA is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.