Description

Bis-Peg7-Pfp Ester CAS NO 1334170-01-2 is a specialized bifunctional polyethylene glycol (PEG) derivative featuring pentafluorophenyl (Pfp) ester reactive groups at both termini. This compound is a critical building block in advanced bioconjugation and polymer chemistry, enabling efficient, high-yield coupling reactions under mild aqueous conditions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostics, and advanced materials sectors for creating precisely functionalized biomolecules, hydrogels, and drug delivery systems.

Application

• Bioconjugation Reagent: For the efficient, site-specific labeling of peptides, proteins, and antibodies with fluorophores, drugs, or other functional molecules.
• Crosslinking Agent: Used in the synthesis of hydrogels, polymer networks, and biomaterials for tissue engineering and controlled release applications.
• Pharmaceutical Intermediate: Serves as a key linker in the development of antibody-drug conjugates (ADCs) and other targeted therapeutic modalities.
• Surface Functionalization: Enables the modification of nanoparticles, biosensors, and chromatographic media with bioactive ligands.
• Polymer Chemistry: Acts as a macro-initiator or chain extender in the synthesis of functionalized block copolymers and dendrimers.
• Diagnostic Assay Development: Facilitates the stable immobilization of capture molecules on solid supports for ELISA and microarray platforms.

Basic Information

Product Name	Bis-Peg7-Pfp Ester
CAS No.	1334170-01-2
Molecular Formula	C38H44F10O16
Molecular Weight	946.74 g/mol
Synonyms	Bis-PEG7-PFP ester; α,ω-Bis(pentafluorophenyl) ester of heptaethylene glycol; PEG7 bis(PFP) ester; Heptaethylene glycol bis(2,3,4,5,6-pentafluorobenzoate); 1,1'-[1,2-Ethanediylbis(oxy-3,6,9,12,15,18,21-heptaoxadocosane-1,22-diyl)] bis(2,3,4,5,6-pentafluorobenzene); PFP-PEG7-PFP; Bis(Pentafluorophenyl) PEG7 ester
EINECS	Contact for details

Quality Control

Our Bis-Peg7-Pfp Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.