Description

Bis-Peg9-Pfp Ester is a specialized bifunctional polyethylene glycol (PEG) derivative featuring pentafluorophenyl (PFP) ester reactive groups. This compound is a critical intermediate for the efficient, high-yield conjugation of amine-containing molecules, enabling the creation of advanced functional materials and bioconjugates. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, high-purity linkers for developing drug delivery systems, diagnostic agents, and cross-linked polymers.

Application

• Bioconjugation & Drug Delivery: A key linker for attaching peptides, proteins, or antibodies to drug molecules, nanoparticles, or solid supports to create targeted therapeutics and diagnostics.
• Polymer & Material Science: Serves as a versatile cross-linking agent or initiator for synthesizing PEG-based hydrogels, smart materials, and surface coatings with tailored properties.
• Proteomics & Diagnostics: Used in the preparation of affinity chromatography resins, microarray surfaces, and labeling reagents for assay development.
• Chemical Biology & Research: An essential tool for modifying biomolecules in vitro, studying protein interactions, and developing novel chemical probes.
• ADC (Antibody-Drug Conjugate) Development: Facilitates the stable and site-specific attachment of cytotoxic payloads to antibodies, a core technology in next-generation oncology treatments.

Basic Information

Product Name	Bis-Peg9-Pfp Ester
CAS No.	1334170-00-1
Molecular Formula	C₄₃H₅₂F₁₀O₂₃
Molecular Weight	1115.85 g/mol
Synonyms	Bis-PEG9-PFP ester; α,ω-Bis(pentafluorophenyl) PEG9 ester; PEG 450 PFP ester; Pentafluorophenyl ester of PEG 450; Poly(ethylene glycol) bis(pentafluorophenyl) ester (n=9); 1,1'-[1,11-dioxo-3,6,9-trioxa-2,10-diazadodecane-1,12-diyl] bis(2,3,4,5,6-pentafluorobenzene); 2,3,4,5,6-Pentafluorophenyl 2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-oate 2,3,4,5,6-pentafluorophenyl ester
EINECS	Contact for details

Quality Control

Our Bis-Peg9-Pfp Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive research and production applications. A detailed Certificate of Analysis (COA) with lot-specific data is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Keep container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Molecular Weight (GPC)	1100 ± 50 g/mol
Functional Group Assay	≥ 90%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.