Description

Acetoxy-Lysylpyridinoline is a chemically modified derivative of the advanced glycation end-product (AGE) biomarker, Lysylpyridinoline. This compound is of significant value as a high-purity reference standard and a critical biochemical tool for research into collagen cross-linking, bone metabolism, and the pathophysiology of diabetes and aging. It is primarily required by analytical laboratories, pharmaceutical R&D departments, and academic institutions focused on developing diagnostic assays and studying connective tissue disorders.

Application

• Biochemical Research Standard: Serves as a certified reference material for the quantification of collagen cross-links in biological samples via LC-MS/MS or HPLC.
• Diagnostic Development: Used in the calibration and validation of clinical diagnostic kits targeting advanced glycation end-products (AGEs) for conditions like diabetes and osteoporosis.
• Pharmaceutical R&D: Employed as a key intermediate or analytical standard in drug discovery programs aimed at inhibiting AGE formation or treating related metabolic diseases.
• Metabolic Studies: A vital tool for in vitro and ex vivo studies investigating bone quality, collagen turnover, and the effects of hyperglycemia on tissue aging.
• Quality Control: Used by manufacturers of diagnostic reagents to ensure batch-to-batch consistency and accuracy of their products.

Basic Information

Product Name	Acetoxy-Lysylpyridinoline
CAS No.	1321573-23-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Acetoxy-LP; N-Acetoxy-Lysylpyridinoline; Acetylated Lysylpyridinoline; Modified Pyridinoline Crosslink; AGE Derivative Standard; Collagen Crosslink Derivative; LP Acetate Ester
EINECS	Contact for details

Quality Control

Our Acetoxy-Lysylpyridinoline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and mass spectrometry, to ensure high purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and chromatographic data is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, consider desiccant and under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 1.0%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.