Description

Tetranor-PGDM-d6 is a deuterium-labeled internal standard used for the precise quantification of prostaglandin metabolites in biological matrices. This compound is critical for ensuring analytical accuracy and reproducibility in quantitative bioanalysis, particularly in liquid chromatography-mass spectrometry (LC-MS/MS) applications. It is an essential tool for researchers and laboratories in the pharmaceutical, clinical diagnostics, and life sciences sectors requiring high-fidelity biomarker measurement.

Application

• LC-MS/MS Internal Standard: Primary application for the accurate quantification of Tetranor-PGDM and related prostaglandin metabolites in complex samples.
• Biomarker Research: Used in studies investigating inflammation, oxidative stress, and related physiological or pathological processes.
• Clinical Diagnostics Development: Supports the development and validation of diagnostic assays for conditions linked to eicosanoid pathway dysregulation.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Studies: Enables precise tracking of drug effects on prostaglandin metabolism in preclinical and clinical research.
• Metabolomics: A key standard in targeted metabolomics panels focusing on the arachidonic acid cascade and eicosanoid profiling.
• Quality Control in Bioanalysis: Serves as a critical component for ensuring data integrity and meeting regulatory standards in GLP/GCP-compliant laboratories.

Basic Information

Product Name	Tetranor-PGDM-d6
CAS No.	1314905-92-4
Molecular Formula	C16H20D6O5
Molecular Weight	304.40 g/mol (approx.)
Synonyms	11,15-Dioxo-9-hydroxy-2,3,4,5-tetranorprostan-1,20-dioic Acid-d6; 9-Hydroxy-11,15-dioxo-2,3,4,5-tetranorprostane-1,20-dioic Acid-d6; Tetranor Prostaglandin D Metabolite-d6; Tetranor-PGDM Methyl Ester-d6 (derivative); 2,3,4,5-Tetranor-PGDM-d6; PGDM Tetranor Metabolite-d6; d6-Tetranor-PGDM
EINECS	Contact for details

Quality Control

Our Tetranor-PGDM-d6 is manufactured under controlled conditions to ensure the highest standards of isotopic purity and chemical integrity. Each batch is subjected to rigorous analytical testing, including NMR and mass spectrometry, to confirm deuteration level and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (e.g., ≥98% D), chemical purity (by HPLC), and batch-specific data is provided to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Isotopic Purity (D)	≥98%
Chemical Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.