Description

(S)-6,6-Dimethyl-Morpholine-3-Carboxylic Acid Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its stereochemically defined morpholine core, which is a privileged scaffold in medicinal chemistry for modulating drug-like properties. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas like oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and approved APIs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to introduce the morpholine pharmacophore.
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor for constructing enantiomerically pure compounds in fine chemical production.
• Protease Inhibitor Development: Potential building block for inhibitors targeting specific enzymes, given the carboxylic acid functionality.
• Chemical Biology Probes: Utilized in the development of tool compounds and molecular probes for biological target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high chiral purity.

Basic Information

Product Name	(S)-6,6-Dimethyl-Morpholine-3-Carboxylic Acid Hydrochloride
CAS No.	1313277-24-5
Molecular Formula	C7H14ClNO3
Molecular Weight	195.65 g/mol
Synonyms	(3S)-6,6-Dimethylmorpholine-3-carboxylic acid hydrochloride; (S)-6,6-Dimethyl-3-morpholinecarboxylic acid hydrochloride; (S)-6,6-Dimethylmorpholine-3-carboxylic acid HCl; 6,6-Dimethylmorpholine-3-carboxylic acid hydrochloride, (S)-; Morpholine-3-carboxylic acid, 6,6-dimethyl-, hydrochloride, (3S)-; (S)-6,6-Dimethyl-tetrahydro-1,4-oxazine-3-carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-6,6-Dimethyl-Morpholine-3-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC to ensure enantiomeric purity, standard identification tests, and stringent control of impurities. A Certificate of Analysis (COA) detailing purity, assay, and related substances is provided with every shipment to guarantee consistent quality and traceability for your critical R&D and cGMP manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.