Description

Biotin-Peg3-Lipoamide CAS NO 1311963-67-3 is a high-purity, heterobifunctional crosslinking reagent that combines the biotin affinity tag with a lipoamide moiety via a triethylene glycol (PEG3) spacer. This molecular design is critical for creating stable, site-specific conjugations in bioconjugation and protein labeling applications, enabling advanced research and diagnostic assay development. It is an essential tool for scientists in pharmaceutical R&D, proteomics, and the development of targeted therapeutics and diagnostic kits who require precise and reliable conjugation chemistry.

Application

• Bioconjugation Reagent: For the site-specific labeling of proteins, antibodies, and peptides with biotin tags.
• Proteomics Research: Used in pull-down assays and affinity purification to isolate and study protein complexes.
• Diagnostic Kit Development: A key component in the manufacture of ELISA, lateral flow assays, and other immunoassays requiring stable biotin-streptavidin interactions.
• Drug Delivery System Conjugation: Facilitates the attachment of targeting ligands to nanoparticles or drug carriers.
• Surface Functionalization: For immobilizing biomolecules on biosensors, microarrays, and other solid supports.
• Chemical Biology Probes: Synthesis of activity-based probes for studying enzyme function and metabolic pathways.

Basic Information

Item	Detail
Product Name	Biotin-Peg3-Lipoamide
CAS No.	1311963-67-3
Molecular Formula	C24H42N4O6S2
Molecular Weight	546.73 g/mol
Synonyms	Biotin-PEG3-Lipoamide; Biotin-PEG3-Lipoamide; 6-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[[5-(1,2-dithiolan-3-yl)pentanoyl]amino]ethoxy]ethoxy]ethyl]hexanamide; Lipoic Acid-PEG3-Biotin; Biotin-PEG3-LA; Biotinylated Lipoamide Linker; Biotin-(PEG)3-Lipoamide
EINECS	Contact for details

Quality Control

Every batch of Biotin-Peg3-Lipoamide is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard quality commitment includes HPLC purity ≥95% (with higher grades available), verification by NMR and mass spectrometry, and stringent control of residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.