Description

n-(2-Sulfoethyl)Maleimide Sodium Salt is a specialized, water-soluble maleimide derivative functionalized with a sulfonate group. This unique bifunctional structure makes it a valuable reagent for bioconjugation and polymer modification, offering enhanced solubility in aqueous systems compared to traditional maleimides. It is primarily used by researchers and manufacturers in the life sciences, polymer chemistry, and materials science sectors for creating stable thioether linkages with sulfhydryl groups under mild conditions.

Application

• Bioconjugation Reagent: For site-specific labeling of proteins, antibodies, and peptides via cysteine residues.
• Polymer Functionalization: As a comonomer or post-polymerization modifier to introduce hydrophilic, anionic, or reactive sites into polymer backbones.
• Hydrogel Synthesis: Crosslinking agent for creating biocompatible and stimuli-responsive hydrogel networks.
• Surface Modification: Immobilization of biomolecules or functional layers onto surfaces for biosensor and diagnostic device development.
• Drug Delivery Systems: Conjugation of therapeutic payloads to carriers like polymers or antibodies for targeted delivery.
• Chromatography Media: Ligand attachment for affinity chromatography columns.

Basic Information

Product Name	n-(2-Sulfoethyl)Maleimide Sodium Salt
CAS No.	1299434-16-4
Molecular Formula	C6H6NNaO5S
Molecular Weight	227.17 g/mol
Synonyms	2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethanesulfonic Acid Sodium Salt; 1-(2-Sulfoethyl)-1H-pyrrole-2,5-dione Sodium Salt; Sodium 1-(2-Sulfoethyl)maleimide; N-(2-Sulfonatoethyl)maleimide Sodium Salt; Maleimide-PEG-Sulfonate; SEMS; Water-Soluble Maleimide Sodium Salt
EINECS	Contact for details

Quality Control

Our n-(2-Sulfoethyl)Maleimide Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and industrial applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility (Water)	Clear, colorless solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.