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7(R)-Maresin 1 CAS NO 1268720-28-0
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CAS No.:1268720-28-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
7(R)-Maresin 1 is a specialized pro-resolving lipid mediator (SPM) derived from the ω-3 fatty acid docosahexaenoic acid (DHA). This compound is of significant interest for its potent and stereospecific biological activity in actively resolving inflammation and promoting tissue regeneration. It is a critical research-grade biochemical for scientists in the fields of immunology, pharmacology, and metabolic disease research. The product is supplied under the CAS registry number 1268720-28-0.
Application
- Biomedical Research: Used as a reference standard and active agent in studies investigating the molecular mechanisms of inflammation resolution.
- Drug Discovery & Development: Serves as a lead compound or pharmacophore model for developing novel anti-inflammatory and pro-healing therapeutics.
- Cell Culture & In Vitro Studies: Applied in cell-based assays to study its effects on macrophage function, neutrophil apoptosis, and tissue repair pathways.
- Metabolic Disorder Research: Investigated for its potential role in modulating insulin sensitivity and resolving inflammation in conditions like obesity and diabetes.
- Neuroscience Research: Explored for neuroprotective effects and its role in resolving neuroinflammation associated with various neurological diseases.
- Wound Healing Models: Used in experimental models to assess the enhancement of tissue regeneration and reduction of chronic inflammation.
Basic Information
| Item | Details |
|---|---|
| Product Name | 7(R)-Maresin 1 |
| CAS No. | 1268720-28-0 |
| Molecular Formula | C22H32O4 |
| Molecular Weight | 360.49 g/mol |
| Synonyms | 7(R)-MaR1; MaR1; (4Z,7R,8E,10E,12Z,14S,16Z,19Z)-7,14-Dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid; 7R,14S-dihydroxy-4Z,8E,10E,12Z,16Z,19Z-docosahexaenoic acid; Maresin-1; Specialized Pro-resolving Mediator MaR1; Resolvin Lipid Mediator |
| EINECS | Contact for details |
Quality Control
Our 7(R)-Maresin 1 is produced under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant standards for research chemicals, and specifications can be provided to meet the stringent requirements of pharmaceutical and academic research.
Storage
Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry, cool, and well-ventilated area.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC/MS) | Conforms to reference standard |
| Purity (HPLC) | ≥ 95% (Area %) |
| Water Content (KF) | ≤ 1.0 % |
| Residual Solvents (GC) | Meets ICH guidelines |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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