Description

(1R,2R)-1,2-Diphenyl-1-Piperidineethanamine is a chiral amine compound featuring a piperidine core flanked by two phenyl groups, serving as a sophisticated building block in advanced organic synthesis. Its precise stereochemistry makes it a valuable intermediate for constructing complex molecules with specific three-dimensional architectures. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry, asymmetric catalysis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of chiral ligands for metal-catalyzed reactions to produce enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for developing novel, stereospecific pesticides and herbicides.
• Academic & Industrial R&D: Employed in chemical research to study reaction mechanisms and develop new synthetic methodologies.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural products, flavors, and fragrances requiring high stereochemical control.

Basic Information

Product Name	(1R,2R)-1,2-Diphenyl-1-Piperidineethanamine
CAS No.	1262516-53-9
Molecular Formula	C19H24N2
Molecular Weight	280.41 g/mol
Synonyms	(1R,2R)-1,2-Diphenyl-2-(piperidin-1-yl)ethanamine; (1R,2R)-1,2-Diphenyl-2-(1-piperidinyl)ethanamine; (1R,2R)-1,2-Diphenyl-1-piperidin-1-ylethanamine; (1R,2R)-1,2-Diphenyl-2-piperidin-1-ylethan-1-amine; 1,2-Diphenyl-1-piperidineethanamine (R,R)-isomer; (R,R)-1,2-Diphenyl-2-(piperidin-1-yl)ethanamine
EINECS	Contact for details

Quality Control

Our (1R,2R)-1,2-Diphenyl-1-Piperidineethanamine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.