Description

Dehydroepiandrosterone-[D6] Sulfate Sodium Salt is a high-purity, deuterium-labeled internal standard critical for advanced analytical quantification. This stable isotope-labeled compound is essential for ensuring the accuracy and reliability of mass spectrometry-based assays by correcting for analyte loss during sample preparation and instrument variability. It is primarily required by pharmaceutical R&D laboratories, clinical research organizations, and contract testing facilities engaged in precise steroid hormone analysis, pharmacokinetic studies, and metabolomics research.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference for the analysis of endogenous DHEA-S and related steroid sulfates in biological matrices like serum, plasma, and urine.
• Clinical Research & Diagnostics: Enables accurate measurement of DHEA-S levels for studies on adrenal function, endocrine disorders, and aging.
• Pharmaceutical Development: Supports bioanalytical method development and validation for drug candidates affecting steroidogenic pathways.
• Metabolomics & Biomarker Discovery: Facilitates precise profiling of steroid sulfate metabolites in complex samples for disease biomarker identification.
• Forensic Toxicology: Aids in the confirmatory testing for exogenous anabolic steroids or endocrine disruptors.
• Quality Control in Reference Material Production: Serves as a calibrant in the manufacture of certified reference materials (CRMs) for clinical assays.

Basic Information

Product Name	Dehydroepiandrosterone-[D6] Sulfate Sodium Salt
CAS No.	1261254-41-4
Molecular Formula	C19H21D6NaO5S
Molecular Weight	396.51 g/mol
Synonyms	DHEA-S-d6 Sodium Salt; 3β-Hydroxy-5-androsten-17-one 3-sulfate-d6 Sodium Salt; 5-Androsten-3β-ol-17-one 3-sulfate-d6 Sodium Salt; Dehydroisoandrosterone Sulfate-d6 Sodium Salt; Prasterone Sulfate-d6 Sodium Salt; Androstenolone Sulfate-d6 Sodium Salt; [16,16,17,17,21,21-2H6]-DHEA-S Sodium Salt
EINECS	Contact for details

Quality Control

Every batch of our Dehydroepiandrosterone-[D6] Sulfate Sodium Salt is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity to meet the exacting demands of quantitative bioanalysis. Comprehensive testing includes assay, isotopic enrichment, and identification by spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to ensure full traceability and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant in the container. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.