Description

Nh-(Peg3-Azide)2 CAS NO 1258939-39-7 is a specialized bifunctional PEG linker featuring dual azide groups, designed for advanced bioconjugation and click chemistry applications. This compound is critical for creating stable, well-defined crosslinks in complex molecular architectures, enabling precise control over material properties and biological interactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and materials science sectors for drug delivery system development, hydrogel formation, and surface functionalization.

Application

• Bioconjugation and Click Chemistry: Serves as a versatile linker for coupling biomolecules (e.g., proteins, peptides, oligonucleotides) via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (SPAAC) reactions.
• Drug Delivery System Fabrication: Used to create PEGylated drug conjugates and crosslinked nanoparticle carriers to enhance solubility, stability, and targeted delivery.
• Hydrogel and Biomaterial Synthesis: Acts as a crosslinking agent to form biocompatible hydrogels for tissue engineering, 3D cell culture, and controlled release matrices.
• Surface Modification and Functionalization: Enables the attachment of bioactive molecules to surfaces (e.g., chips, beads, implants) for biosensing, diagnostic assays, and improved biocompatibility.
• Polymer and Dendrimer Chemistry: A key building block for synthesizing functionalized polymers and dendrimers with tailored properties for advanced material applications.
• Antibody-Drug Conjugate (ADC) Development: Facilitates the stable linkage between cytotoxic payloads and antibodies, a core technology in modern oncology therapeutics.

Basic Information

Product Name	Nh-(Peg3-Azide)2 CAS NO 1258939-39-7
CAS No.	1258939-39-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1,11-Bis(azido)-3,6,9-trioxaundecane; Bis(PEG3-azide); 1-Azido-3,6,9-trioxaundecan-11-yl azide; PEG3-diazide; 2,2'-(Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) diazide; Azido-PEG3-azide; 1,11-Diazido-3,6,9-trioxaundecane; NH(PEG3-N3)2
EINECS	Contact for details

Quality Control

Our Nh-(Peg3-Azide)2 is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.