Description

(R)-3-tert-Butoxy-2-Hydroxypropanoic Acid is a high-purity chiral building block of significant importance in asymmetric synthesis. This compound matters as a versatile intermediate for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new drugs, catalysts, and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for cardiovascular and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry enhances efficacy and reduces environmental impact.
• Catalyst & Ligand Preparation: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric hydrogenation and carbon-carbon bond formation reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high enantiomeric purity.
• Academic & Industrial Research: A valuable tool for chemists in process development and methodology research focused on stereoselective synthesis.

Basic Information

Product Name	(R)-3-tert-Butoxy-2-Hydroxypropanoic Acid
CAS No.	1258418-91-5
Molecular Formula	C7H14O4
Molecular Weight	162.18 g/mol
Synonyms	(R)-3-(tert-Butoxy)-2-hydroxypropanoic acid; (R)-2-Hydroxy-3-(tert-butoxy)propanoic acid; (R)-3-(tert-Butoxy)-2-hydroxypropionic acid; (R)-2-Hydroxy-3-tert-butoxypropionic acid; (R)-O-tert-Butyl-D-glyceric acid; D-3-tert-Butoxy-2-hydroxypropanoic acid; (R)-Glyceric acid tert-butyl ether; (2R)-3-(tert-Butoxy)-2-hydroxypropanoic acid
EINECS	Contact for details

Quality Control

Our (R)-3-tert-Butoxy-2-Hydroxypropanoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure compliance with high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.