Description

(1R)-1-Cyclobutylethan-1-Ol CAS NO 1257214-06-4 is a chiral secondary alcohol featuring a cyclobutyl substituent, serving as a valuable chiral building block and intermediate in advanced organic synthesis. Its defined stereochemistry is critical for imparting specific biological activity and physical properties to target molecules. This compound is primarily needed by pharmaceutical research and development organizations, agrochemical innovators, and specialty chemical manufacturers for applications in asymmetric synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric catalytic reactions.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing chiral aroma chemicals with specific olfactory profiles.
• Material Science Research: Employed in the synthesis of chiral monomers for advanced polymeric materials.
• Academic and R&D Laboratories: A valuable reference standard and building block for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(1R)-1-Cyclobutylethan-1-Ol
CAS No.	1257214-06-4
Molecular Formula	C6H12O
Molecular Weight	100.16 g/mol
Synonyms	(R)-1-Cyclobutylethanol; (1R)-1-Cyclobutylethanol; (R)-(-)-1-Cyclobutylethanol; (R)-1-Cyclobutyl-1-ethanol; (R)-α-Methylcyclobutylmethanol; (1R)-1-Cyclobutyl-1-hydroxyethane; (R)-Cyclobutylmethylcarbinol; (R)-CBEM
EINECS	Contact for details

Quality Control

Our (1R)-1-Cyclobutylethan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for research and process development. Certificates of Analysis (COA) detailing identity, purity (HPLC/GC), chiral excess (Chiral HPLC), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.