Description

Citalopram-D6 Oxalate is a high-purity, deuterium-labeled internal standard critical for modern analytical chemistry. This stable isotope-labeled compound is essential for ensuring the accuracy and reliability of quantitative analyses, particularly in mass spectrometry. It is primarily used by pharmaceutical R&D laboratories, contract research organizations (CROs), and regulatory testing facilities for method development, validation, and bioanalytical studies of the antidepressant citalopram.

Application

• Quantitative Mass Spectrometry: Serves as an internal standard for the precise and accurate quantification of citalopram and its metabolites in complex biological matrices (e.g., plasma, serum, urine) using LC-MS/MS and GC-MS.
• Pharmacokinetic & Bioequivalence Studies: Enables reliable measurement of drug concentration-time profiles in clinical and preclinical trials to determine absorption, distribution, metabolism, and excretion (ADME) parameters.
• Forensic & Clinical Toxicology: Used in analytical methods for the definitive identification and quantification of citalopram in post-mortem and compliance testing scenarios.
• Pharmaceutical Quality Control: Supports impurity profiling and assay validation for drug substance and finished product testing in GMP environments.
• Metabolite Identification & Profiling: Aids in the detection and structural elucidation of citalopram metabolites in in vitro and in vivo studies.
• Environmental & Food Safety Analysis: Applied in trace-level detection methods for pharmaceutical residues in environmental waters and food products.

Basic Information

Product Name	Citalopram-D6 Oxalate
CAS No.	1246819-94-2
Molecular Formula	C20H15D6FN2O • C2H2O4
Molecular Weight	447.48 g/mol
Synonyms	1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile-D6 Oxalate; (+/-)-Citalopram-D6 Oxalate; Citalopram-d6 (1,1,2,2,3,3-hexadeuterio) Oxalate; 1-[3-(Dimethylamino)propyl]-1-(p-fluorophenyl)-5-phthalancarbonitrile-D6 Oxalate; Citalopram D6 Oxalate Salt; Deuterated Citalopram Oxalate
EINECS	Contact for details

Quality Control

Every batch of Citalopram-D6 Oxalate is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR, MS, and HPLC. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity (typically ≥98% by HPLC), isotopic enrichment (≥98 atom % D), and conformity to customer specifications. Our quality commitment supports compliance with ISO, GMP, and other relevant regulatory frameworks for research and diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant and inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0%
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.