Description

Des-4-Fluorobenzyl Mosapride-D5 is a deuterated analog of a key mosapride metabolite, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity reference material is critical for ensuring the accuracy and reliability of pharmacokinetic and bioanalytical studies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities specializing in method development and validation.

Application

• Internal Standard for LC-MS/MS: Essential for the precise quantification of mosapride and its metabolites in complex biological matrices like plasma, serum, and urine.
• Pharmaceutical Research & Development: Supports drug metabolism and pharmacokinetics (DMPK) studies during the development of gastroprokinetic agents.
• Bioanalytical Method Validation: Used to develop and validate robust, GLP-compliant analytical methods for clinical and non-clinical trials.
• Metabolite Profiling: Aids in the identification and quantification of specific metabolic pathways in in vitro and in vivo studies.
• Quality Control in Reference Material Production: Serves as a critical calibrant for ensuring the quality of other certified reference materials.

Basic Information

Product Name	Des-4-Fluorobenzyl Mosapride-D5
CAS No.	1246814-79-8
Molecular Formula	C21H20D5FN4O3
Molecular Weight	~ 401.5 g/mol
Synonyms	4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]-D5-benzamide; Mosapride Metabolite M-4-D5; 4-Fluorobenzyl Mosapride Deuterated Standard; Des-4-Fluorobenzyl Mosapride (d5); Deuterated Mosapride Carboxylic Acid Metabolite
EINECS	Contact for details

Quality Control

Our Des-4-Fluorobenzyl Mosapride-D5 is manufactured under strict quality systems to ensure the high chemical purity and isotopic enrichment required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for identity, purity (by HPLC), isotopic purity (D-content), and related substances. We adhere to relevant industry standards for reference materials to ensure reliable and reproducible performance in your laboratory.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (Mass Spectrometry)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (by NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.