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n-[11-(Dipyrrometheneboron Difluoride)Undecanoyl]-D-Glucosyl-1-1'-D-Erythro-Sphingosine CAS NO 1246355-70-3
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CAS No.:1246355-70-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-[11-(Dipyrrometheneboron Difluoride)Undecanoyl]-D-Glucosyl-1-1'-D-Erythro-Sphingosine is a sophisticated, fluorescently labeled sphingolipid derivative designed for advanced biochemical research and diagnostic applications. This compound is engineered to act as a highly sensitive fluorescent probe for tracking and visualizing sphingolipid metabolism, membrane dynamics, and cellular processes in real-time. It is an essential tool for researchers in pharmaceutical development, cell biology, and diagnostic assay design who require precise, high-contrast imaging agents.
Application
- Fluorescent Labeling of Sphingolipids: Used as a vital probe for studying the synthesis, trafficking, and degradation of sphingolipids within live cells.
- Live-Cell Imaging: Enables real-time visualization of membrane microdomains (lipid rafts), endocytosis, and intracellular signaling pathways.
- Diagnostic Assay Development: Serves as a key component in the development of high-throughput screening (HTS) assays and fluorescence-based diagnostic kits for metabolic disorders.
- Pharmaceutical Research: Utilized in drug discovery to investigate the mechanisms of action of compounds targeting sphingolipid-related pathways in cancer, neurology, and inflammation.
- Biophysical Studies: Applied in model membrane systems (e.g., liposomes) to study lipid-protein interactions and membrane fluidity using fluorescence spectroscopy.
Basic Information
| Product Name | n-[11-(Dipyrrometheneboron Difluoride)Undecanoyl]-D-Glucosyl-1-1'-D-Erythro-Sphingosine |
| CAS No. | 1246355-70-3 |
| Molecular Formula | C52H81BF2N2O9 |
| Molecular Weight | 926.99 g/mol |
| Synonyms | BODIPY®-FL C12-Sphingosine; BODIPY® FL C12-Glucosylceramide; Fluorescent Glucosylceramide; BODIPY® 493/503-labeled Glucosylceramide; N-{11-[5-(4,4-Difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene-2-yl)penta-2,4-dienoyl]amino}undecanoyl-D-glucosyl-β1-1'-D-erythro-sphingosine; BODIPY® FL C5-Ceramide (GlcCer derivative); Fluorescent Sphingolipid Probe |
| EINECS | Contact for details |
Quality Control
Our production of this high-purity biochemical adheres to stringent quality protocols. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and fluorescent performance. A comprehensive Certificate of Analysis (COA) detailing assay purity, impurity profile, and spectral properties is provided with every shipment to ensure traceability and support your research integrity.
Storage
Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation. Solutions prepared in DMSO or other appropriate solvents should be aliquoted and stored under inert atmosphere to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | Orange to red solid or film |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Extinction Coefficient (ε) | ~90,000 cm-1M-1 at ~503 nm |
| Fluorescence Emission | ~510-515 nm |
| Solubility | Soluble in DMSO, DMF, ethanol |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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