Description

1-Palmitoyl-2-(Dipyrrometheneboron Difluoride)Undecanoyl-Sn-Glycero-3-Phospho-L-Serine (Ammonium Salt) is a sophisticated, fluorescently labeled phospholipid probe designed for advanced membrane biophysics and cell biology research. This compound matters because it integrates the exceptional photostability and brightness of a BODIPY fluorophore directly into the sn-2 acyl chain of phosphatidylserine, enabling precise, non-perturbative tracking of lipid dynamics and membrane asymmetry. It is critically needed by researchers in pharmaceutical R&D, academic biochemistry, and diagnostic development for applications in lipidomics, apoptosis studies, and the development of lipid nanoparticle (LNP) delivery systems.

Application

• Membrane Biophysics Research: As a fluorescent phosphatidylserine (PS) analog for studying lipid bilayer properties, phase separation (lipid rafts), and flip-flop kinetics in model membranes.
• Cell Biology & Apoptosis Assays: For the sensitive detection and visualization of phosphatidylserine externalization on the outer leaflet of the plasma membrane, a key hallmark of programmed cell death.
• Lipid Nanoparticle (LNP) Formulation & Tracking: To fluorescently label and monitor the fate, cellular uptake, and intracellular trafficking of therapeutic LNPs used in mRNA and gene delivery.
• Lipidomics & Metabolic Tracing: As a stable, fluorescent tracer to investigate PS metabolism, intracellular transport, and enzymatic remodeling pathways within living cells.
• High-Content Screening (HCS): Enabling automated, image-based screening assays for drug discovery targets related to membrane biology and cell death pathways.
• Development of Diagnostic Kits: Serving as a critical component in the development of advanced fluorescence-based assays for clinical and research diagnostics.

Basic Information

Item	Detail
Product Name	1-Palmitoyl-2-(Dipyrrometheneboron Difluoride)Undecanoyl-Sn-Glycero-3-Phospho-L-Serine (Ammonium Salt)
CAS No.	1246355-65-6
Molecular Formula	C49H81BF2N3O10P
Molecular Weight	~960.0 g/mol
Synonyms	BODIPY® FL C11-PS; Fluorescent Phosphatidylserine; BODIPY FL Phosphatidylserine; 1-Palmitoyl-2-(BODIPY® FL C11)-sn-glycero-3-phosphoserine (ammonium salt); BODIPY® 500/510 C11, 1-Palmitoyl-2-{BODIPY® FL C11}-sn-Glycero-3-Phospho-L-Serine; TopFluor® PS; Fluorescent PS analog; BODIPY FL-labeled PS
EINECS	Contact for details

Quality Control

Every batch of our 1-Palmitoyl-2-(Dipyrrometheneboron Difluoride)Undecanoyl-Sn-Glycero-3-Phospho-L-Serine (Ammonium Salt) is synthesized and purified under stringent conditions to ensure the highest standards of chemical purity and fluorescent performance. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting identity, purity, and spectral properties to support your critical research and development.

Storage

Preserve in a tightly closed container, protected from light. This product is strictly light-sensitive (protect from all light exposure) and hygroscopic (moisture-sensitive). For long-term stability, store desiccated at -20°C or below. Under these conditions, the product is typically stable for at least 24 months. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Orange to red solid or film
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with molecular structure
Purity (HPLC)	≥ 95% (Area % at specified wavelength)
Excitation Maximum (λex)	~500 nm
Emission Maximum (λem)	~510 nm
Solubility	Soluble in chloroform, methanol, DMSO; forms micelles in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.