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1-Palmitoyl-2-(Dipyrrometheneboron Difluoride)Undecanoyl-Sn-Glycero-3-Phosphocholine CAS NO 1246355-63-4
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CAS No.:1246355-63-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-Palmitoyl-2-(Dipyrrometheneboron Difluoride)Undecanoyl-Sn-Glycero-3-Phosphocholine is a sophisticated, fluorescently labeled phospholipid probe designed for advanced membrane biophysics and cell biology research. This compound matters because it integrates a highly photostable BODIPY fluorophore directly into the lipid structure, enabling precise, non-perturbative tracking of lipid dynamics and membrane organization. Researchers in pharmaceutical development, biochemistry, and advanced materials science need this high-purity reagent for applications such as fluorescence microscopy, flow cytometry, and the study of lipid rafts, vesicle trafficking, and membrane fusion processes.
Application
- Fluorescent Cell Membrane Labeling: For real-time visualization of plasma membrane dynamics, endocytosis, and exocytosis in live-cell imaging.
- Lipid Raft and Microdomain Studies: As a probe to investigate the organization and fluidity of membrane microdomains due to its specific partitioning properties.
- Liposome and Model Membrane Research: Incorporation into liposomes and giant unilamellar vesicles (GUVs) for in vitro studies of membrane properties and interactions.
- Flow Cytometry Applications: Used to label cell membranes for high-throughput analysis and sorting based on membrane characteristics.
- Drug Delivery System Development: As a traceable component in the formulation and tracking of lipid-based nanoparticle drug carriers.
- Biophysical Assays: Employed in fluorescence resonance energy transfer (FRET) or fluorescence recovery after photobleaching (FRAP) experiments to measure lipid diffusion and interactions.
Basic Information
| Product Name | 1-Palmitoyl-2-(Dipyrrometheneboron Difluoride)Undecanoyl-Sn-Glycero-3-Phosphocholine |
| CAS No. | 1246355-63-4 |
| Molecular Formula | C55H95BF2N2O9P |
| Molecular Weight | ~1003.19 g/mol |
| Synonyms | BODIPY® FL C11-PC; 1-Palmitoyl-2-(BODIPY® FL C11)-sn-Glycero-3-Phosphocholine; BODIPY® FL Phosphatidylcholine; Fluorescent PC Lipid; BODIPY® 500/510 C1, C12 Phosphatidylcholine; 2-(BODIPY® FL C11)-PC; 1-Palmitoyl-2-(4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Undecanoyl)-sn-Glycero-3-Phosphocholine |
| EINECS | Contact for details |
Quality Control
This high-value biochemical is produced under strict quality control protocols to ensure batch-to-batch consistency and optimal performance. Each lot is characterized using advanced analytical techniques including HPLC, mass spectrometry, and NMR to confirm identity, purity, and fluorescent properties. A comprehensive Certificate of Analysis (COA) detailing purity, absorbance/emission profiles, and solvent content is provided with every shipment to support your critical research and development work.
Storage
Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to warm to room temperature before opening to minimize condensation and moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | Orange to red solid or film |
| Identification (HPLC/MS) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Absorption Maximum (λabs) | ~500 nm |
| Emission Maximum (λem) | ~510 nm |
| Solvent (if supplied in solution) | Chloroform or Ethanol (Contact for details) |
| Water Content (Karl Fischer) | < 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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