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1-Palmitoyl-2-[16-(Acryloyloxy)Palmitoyl]-Sn-Glycero-3-Phosphorylcholine CAS NO 1246304-43-7


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CAS No.:1246304-43-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Palmitoyl-2-[16-(Acryloyloxy)Palmitoyl]-Sn-Glycero-3-Phosphorylcholine is a synthetic, photo-polymerizable phospholipid derivative, a key building block in advanced biomaterials. This compound matters for its unique ability to form stable, biomimetic membranes and hydrogels upon UV light exposure, enabling precise spatial and temporal control in material fabrication. It is essential for researchers and product developers in the pharmaceutical, biomedical engineering, and nanotechnology sectors who require sophisticated, responsive lipid-based platforms for drug delivery, tissue engineering, and diagnostic applications.

Application

  • Biomedical Hydrogels & Scaffolds: As a critical monomer for creating photo-crosslinkable, phospholipid-based hydrogels used in 3D cell culture, wound healing matrices, and tissue engineering scaffolds.
  • Advanced Drug Delivery Systems: For the development of light-triggered liposomes, nanoparticles, and micelles that can release therapeutic payloads (e.g., anticancer drugs, nucleic acids) with precise spatial control.
  • Biosensor & Diagnostic Platforms: Serving as a functional coating or membrane matrix to enhance the biocompatibility and specificity of sensor surfaces for detecting biomarkers or pathogens.
  • Model Membrane Studies: Used in biophysical research to create stable, polymerizable supported lipid bilayers (SLBs) for studying membrane protein function, lipid rafts, and membrane dynamics.
  • Surface Modification & Biointerfaces: To engineer non-fouling, cell-adhesive, or stimuli-responsive surfaces on medical devices, implants, and lab-on-a-chip microfluidic systems.
  • Nanotechnology & Materials Science: As a building block for creating smart, self-assembling nanomaterials with tunable mechanical and chemical properties.

Basic Information

Product Name 1-Palmitoyl-2-[16-(Acryloyloxy)Palmitoyl]-Sn-Glycero-3-Phosphorylcholine
CAS No. 1246304-43-7
Molecular Formula C₄₇H₉₀NO₉P
Molecular Weight 856.19 g/mol
Synonyms Polymerizable PC Lipid; Acryloyl Phosphatidylcholine; 1-Palmitoyl-2-(16-acryloyloxy-palmitoyl)-sn-glycero-3-phosphocholine; Acyl-PC; Photo-PC; Acrylated Phospholipid; PDPC; PC-Acrylate; Light-sensitive Phosphatidylcholine Derivative
EINECS Contact for details

Quality Control

Every batch of our 1-Palmitoyl-2-[16-(Acryloyloxy)Palmitoyl]-Sn-Glycero-3-Phosphorylcholine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and performance consistency for your critical research and development. Certificates of Analysis (COA) with detailed specifications from HPLC, NMR, and MS are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Once opened, use immediately or re-purge the container with inert gas before resealing.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (NMR) Conforms to structure
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 95% (Area %)
Solubility Soluble in chloroform, DCM, DMSO; sparingly soluble in alcohols
Residual Solvents (GC) Meets ICH guidelines
Peroxide Value < 5 mEq/kg
Water Content (KF) < 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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