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1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanolamine-n-{6-[(Cyanur)Amino]Hexanoyl} (Sodium Salt) CAS NO 1246304-36-8
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CAS No.:1246304-36-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanolamine-n-{6-[(Cyanur)Amino]Hexanoyl} (Sodium Salt) is a specialized, functionalized phospholipid derivative designed for advanced bioconjugation and drug delivery applications. Its core value lies in the unique cyanurylaminohexanoyl linker, which provides a reactive handle for covalent attachment to biomolecules, enabling the creation of targeted liposomal and nanoparticle systems. This high-purity synthetic lipid is essential for researchers and formulators in the pharmaceutical and biotechnology sectors developing next-generation therapeutics, including targeted cancer treatments, vaccines, and diagnostic agents. The compound is supplied as a sodium salt to enhance solubility and handling characteristics.
Application
- Targeted Drug Delivery Systems: As a key functional component in the synthesis of ligand-targeted liposomes for oncology and other therapeutic areas.
- Bioconjugation & Probe Development: The cyanurylamino group serves as a versatile site for attaching peptides, antibodies, or other targeting moieties to lipid-based carriers.
- Vaccine Adjuvant Formulations: Used in the design of novel lipid-based adjuvants to enhance immune response.
- Diagnostic Imaging Agents: Incorporation into lipid nanoparticles for the delivery of contrast agents or radiotracers.
- Gene Therapy Vectors: A component in the formulation of lipid nanoparticles (LNPs) for nucleic acid delivery.
- Biomimetic Membrane Research: Used in model membrane studies to investigate cell surface interactions and signaling.
- Surface Functionalization: For modifying material surfaces to create biocompatible or bioactive coatings.
Basic Information
| Product Name | 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanolamine-n-{6-[(Cyanur)Amino]Hexanoyl} (Sodium Salt) |
| CAS No. | 1246304-36-8 |
| Molecular Formula | C48H88N5O11PNa |
| Molecular Weight | 972.19 g/mol |
| Synonyms | DPPE-CYA; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(6-((cyanuryl)amino)hexanoyl) sodium salt; Cyanurylamino-DPPE; N-(6-(Cyanurylamino)hexanoyl)-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine sodium salt; DPPE-Cyanur; Functionalized DPPE; Bioconjugatable DPPE; Phospholipid-cyanuryl conjugate |
| EINECS | Contact for details |
Quality Control
Our 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanolamine-n-{6-[(Cyanur)Amino]Hexanoyl} (Sodium Salt) is manufactured under strict quality systems suitable for research and pharmaceutical development. Each batch undergoes comprehensive analytical characterization including HPLC for purity, NMR for structural confirmation, and mass spectrometry to ensure identity and consistency. We provide full traceability and Certificates of Analysis (COA) detailing all critical quality attributes. Our production adheres to cGMP principles where required, supporting your regulatory filings.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to ensure long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid or powder |
| Identification (HPLC/MS) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 2.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
| Heavy Metals | < 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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