Description

n-Lignoceroyl-D-Erythro-Dihydroceramide-1-Phosphate (Ammonium Salt) is a high-purity, synthetic sphingolipid derivative, specifically a phosphorylated dihydroceramide analogue. This compound is of significant value in advanced biomedical research for its role as a key intermediate and bioactive molecule in studying sphingolipid metabolism and signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and specialty chemical manufacturers focused on lipidomics, drug discovery, and the development of novel therapeutic agents targeting cellular membranes and signaling cascades.

Application

• Biomedical Research: As a critical standard and reagent in lipidomics for the quantification and study of sphingolipid metabolic pathways.
• Drug Discovery: Serving as a key intermediate or a bioactive target molecule in the development of novel therapeutics for cancer, inflammatory, and metabolic diseases.
• Cell Signaling Studies: Used to investigate the role of ceramide-1-phosphate and its analogues in cellular processes like apoptosis, proliferation, and inflammation.
• Enzyme Substrate/Inhibitor: Employed as a specific substrate or inhibitor for enzymes involved in sphingolipid biosynthesis and degradation, such as ceramide kinases.
• Lipid Membrane Research: Utilized in biophysical studies to understand the incorporation and effects of complex sphingolipids on membrane structure, fluidity, and domain formation.
• Reference Standard: Acts as a high-purity analytical standard for method development and validation in LC-MS, HPLC, and other chromatographic techniques.

Basic Information

Product Name	n-Lignoceroyl-D-Erythro-Dihydroceramide-1-Phosphate (Ammonium Salt)
CAS No.	1246303-18-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Dihydroceramide-1-phosphate (C24:0, D-erythro, Ammonium Salt); C24 Dihydroceramide-1-phosphate; Lignoceroyl Dihydroceramide Phosphate; (2S,3R)-2-[(2R,3E)-2-Hydroxy-3-tetracosenamido]-3-hydroxypropyl Dihydrogen Phosphate Ammonium Salt; Ceramide-1-phosphate analogue; D-erythro-C24 Dihydroceramide-1-P; Ammonium (2S,3R)-2-[(2R,3E)-2-hydroxy-3-tetracosenamido]-3-hydroxypropyl phosphate; Synthetic Sphingolipid Phosphate Ester
EINECS	Contact for details

Quality Control

Our n-Lignoceroyl-D-Erythro-Dihydroceramide-1-Phosphate (Ammonium Salt) is manufactured under strict quality control protocols to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to support regulatory requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.