Description

1,2-Dioctanoyl-Sn-Glycero-3-Phospho-(1'-Myo-Inositol-4'-Phosphate) (Ammonium Salt) is a high-purity, synthetic phospholipid derivative of phosphatidylinositol monophosphate (PIP), specifically PI(4)P. This compound serves as a critical biochemical tool and a potential synthetic intermediate for advanced lipid research and development. It is essential for researchers and manufacturers in the life sciences sector, particularly in signal transduction studies, membrane biophysics, and the development of lipid-based drug delivery systems. The ammonium salt form enhances its stability and solubility in aqueous buffers for experimental use.

Application

• Biochemical Research & Standard: Used as a high-purity reference standard and substrate in enzymatic assays to study phosphoinositide kinases, phosphatases, and phospholipases.
• Cell Signaling Studies: A vital tool for investigating intracellular signaling pathways mediated by phosphatidylinositol phosphates (PIPs), particularly those involving PI(4)P.
• Lipidomics & Analytical Standards: Serves as a critical calibrant and internal standard in mass spectrometry-based lipidomic profiling to identify and quantify cellular phosphoinositides.
• Membrane Biophysics: Employed in model membrane systems (e.g., liposomes, lipid bilayers) to study protein-lipid interactions and membrane dynamics.
• Pharmaceutical Development: Investigated as a potential synthetic intermediate or functional component in the design of novel lipid-based therapeutics and targeted drug delivery vehicles.
• Diagnostic Reagent Formulation: May be utilized in the development of specialized diagnostic kits that detect or quantify enzymes or metabolites in the phosphoinositide pathway.

Basic Information

Product Name	1,2-Dioctanoyl-Sn-Glycero-3-Phospho-(1'-Myo-Inositol-4'-Phosphate) (Ammonium Salt)
CAS No.	1246303-11-6
Molecular Formula	C29H57NO16P2 • xNH3
Molecular Weight	Contact for details
Synonyms	PI(4)P (C8); 1,2-Di-O-octanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4-phosphate) ammonium salt; DOPI(4)P; C8-PI(4)P; Phosphatidylinositol 4-phosphate (C8:0); 1,2-Dioctanoylphosphatidylinositol 4-phosphate ammonium salt; sn-Glycero-3-phospho-1D-myo-inositol 4-phosphate, 1,2-dioctanoate, ammonium salt
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. For this high-purity biochemical, quality is assured through advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. We adhere to a cGMP-compliant mindset in our manufacturing processes for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in chloroform/methanol mixtures, slightly soluble in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.