Description

n-Palmitoyl-1-Desoxymethylsphingosine (M17:1/16:0) is a high-purity synthetic sphingolipid derivative, specifically a ceramide analog. This compound is a critical biochemical tool and building block for advanced research in lipidomics, membrane biophysics, and cell signaling pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and cosmetic industries who require well-defined, structurally precise lipids for formulation, drug delivery, and mechanistic studies.

Application

• Biochemical Research: Used as a standard or substrate in studies of sphingolipid metabolism, ceramide-mediated apoptosis, and lipid raft dynamics.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel therapeutics targeting skin diseases, cancer, and inflammatory disorders.
• Cosmetic Science: Incorporated into high-end skincare formulations for its biomimetic properties, helping to restore the skin's natural barrier function and improve hydration.
• Lipidomics & Analytical Standards: Employed as a quantitative internal standard or reference material in mass spectrometry-based lipid profiling and analytical method development.
• Cell Culture & Media Supplements: Used to modulate cell membrane properties and study the effects of specific lipid species on cell behavior and signaling.
• Drug Delivery Systems: Investigated as a component of lipid nanoparticles (LNPs) and other advanced delivery vehicles to enhance stability and targeting.

Basic Information

Product Name	n-Palmitoyl-1-Desoxymethylsphingosine (M17:1/16:0)
CAS No.	1246298-57-6
Molecular Formula	C34H67NO3
Molecular Weight	537.90 g/mol
Synonyms	N-(Hexadecanoyl)-1-desoxymethylsphingosine; Ceramide (d18:1/16:0) Desmethyl Analog; M17:1/16:0 Ceramide; Palmitoyl Desoxymethylsphingosine; 1-Desoxymethylsphingosine Palmitate; N-Palmitoyl-1-desoxymethyl-D-erythro-sphingosine; Sphingosine, N-palmitoyl-1-desoxymethyl-
EINECS	Contact for details

Quality Control

Every batch of n-Palmitoyl-1-Desoxymethylsphingosine (M17:1/16:0) is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We ensure compliance with stringent internal specifications for identity, purity, and stability. A detailed Certificate of Analysis (COA) is provided with each shipment, containing data from HPLC, NMR, and Mass Spectrometry analyses.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.