Description

n-Lauroyl-1-Desoxymethylsphingosine (M17:1/12:0) is a high-purity, synthetic sphingolipid analog, a critical building block for advanced biochemical research and development. This compound is valued for its role in modulating cellular signaling pathways, particularly those related to apoptosis, proliferation, and inflammation. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, lipidomics, and the study of ceramide-related metabolic processes.

Application

• Biochemical Research: A key standard and reagent in lipidomics for the identification and quantification of complex sphingolipids in biological samples.
• Drug Discovery & Development: Used as a precursor or intermediate in the synthesis of novel therapeutic agents targeting sphingolipid metabolism for cancer, neurodegenerative, and inflammatory diseases.
• Cell Signaling Studies: Employed to investigate the role of specific ceramide species in cellular processes like programmed cell death (apoptosis), senescence, and stress response.
• Enzyme Activity Assays: Serves as a substrate or inhibitor in enzymatic studies to characterize the activity of ceramidases, sphingomyelinases, and other lipid-modifying enzymes.
• Cosmeceutical R&D: Investigated for potential applications in advanced skincare formulations aimed at improving skin barrier function and cellular communication.

Basic Information

Product Name	n-Lauroyl-1-Desoxymethylsphingosine (M17:1/12:0)
CAS No.	1246298-55-4
Molecular Formula	C30H59NO3
Molecular Weight	481.80 g/mol
Synonyms	N-[(2S,3R)-1,3-Dihydroxyoctadec-4-en-2-yl]dodecanamide; Lauroylsphingosine; C12-Ceramide (d18:1/12:0); N-Dodecanoylsphingosine; (2S,3R,4E)-2-Dodecanoylamino-4-octadecene-1,3-diol; M17:1/12:0 Ceramide; 1-Desoxymethylsphingosine Lauroyl Ester
EINECS	Contact for details

Quality Control

Our n-Lauroyl-1-Desoxymethylsphingosine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material for GLP or GMP-regulated research upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic nature, the container should be allowed to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (Mass Spec)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.