Description

n-(2'-(S)-Hydroxynervonoyl)-D-Erythro-Sphingosine is a high-purity, synthetic sphingolipid derivative, a critical building block for advanced biochemical research and pharmaceutical development. This compound is essential for studying cell membrane structure, signal transduction pathways, and lipid metabolism, offering researchers a defined and reliable standard. It is primarily utilized by scientists and manufacturers in the life sciences sector, particularly in lipidomics research, drug discovery for metabolic and neurological disorders, and the development of novel therapeutic agents and diagnostic tools.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in lipidomics and metabolomics studies to identify and quantify complex biological lipids.
• Cell Signaling Studies: Investigates the role of sphingolipids in apoptosis, cell proliferation, and stress response pathways.
• Pharmaceutical Intermediates: Serves as a key synthetic precursor for novel drug candidates targeting sphingolipid-related diseases.
• Membrane Biophysics: Employed in model membrane systems to study lipid raft formation, membrane fluidity, and protein-lipid interactions.
• Neuroscience Research: Applied in research focused on myelin formation, neuronal development, and neurodegenerative conditions.
• Cosmeceutical Development: Explored for potential applications in advanced skincare formulations targeting skin barrier function and ceramide replenishment.

Basic Information

Product Name	n-(2'-(S)-Hydroxynervonoyl)-D-Erythro-Sphingosine
CAS No.	1246298-51-0
Molecular Formula	C42H81NO4
Molecular Weight	664.1 g/mol
Synonyms	2-Hydroxynervonoyl Sphingosine; (2S)-2-Hydroxytetracos-15-enoylsphingosine; D-erythro-Sphingosine, N-[(2S)-2-hydroxytetracos-15-enoyl]-; N-[(2S)-2-Hydroxytetracos-15-enoyl]-D-erythro-sphingosine; N-(2'-Hydroxynervonoyl)-D-erythro-sphingosine; Ceramide (d18:1/24:1(2OH)); Hydroxynervonoyl Ceramide; Nervonoyl α-hydroxy fatty acid sphingosine
EINECS	Contact for details

Quality Control

Our n-(2'-(S)-Hydroxynervonoyl)-D-Erythro-Sphingosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with the standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The material is hygroscopic (moisture-sensitive) and must be handled in a dry environment to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.