Description

n-(2'-(S)-Hydroxybehenoyl)-D-Erythro-Sphingosine is a high-purity, synthetic sphingolipid derivative, specifically a ceramide analog featuring a (S)-hydroxybehenic acid moiety. This compound is of significant value in advanced research and development for its role as a critical building block in lipid biochemistry and membrane studies. It is primarily needed by pharmaceutical, biotechnology, and advanced cosmetic R&D sectors for applications in drug delivery systems, skin barrier function research, and the synthesis of complex bioactive lipids.

Application

• Pharmaceutical Research: A key intermediate in the synthesis of novel ceramide-based therapeutics and prodrugs targeting metabolic and inflammatory pathways.
• Cosmetic Science: Used in the development of high-end skincare formulations aimed at restoring and enhancing the skin's natural lipid barrier for improved hydration and protection.
• Biomembrane Studies: Serves as a standard or probe in biophysical research to study lipid raft formation, membrane fluidity, and cell signaling mechanisms.
• Drug Delivery Systems: Incorporated into liposomal and nanoparticle formulations to improve stability, targeting, and cellular uptake of active pharmaceutical ingredients.
• Biochemical Reagent: Utilized as a substrate or inhibitor in enzymatic assays related to sphingolipid metabolism, such as studies on ceramidases and sphingomyelinases.
• Reference Standard: Acts as a certified reference material (CRM) for quality control and analytical method development in laboratories.

Basic Information

Product Name	n-(2'-(S)-Hydroxybehenoyl)-D-Erythro-Sphingosine
CAS No.	1246298-49-6
Molecular Formula	C44H87NO5
Molecular Weight	710.18 g/mol
Synonyms	(2S)-2-Hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]docosanamide; Ceramide AP; N-(2'-Hydroxybehenoyl)-D-erythro-sphingosine; (S)-2-Hydroxybehenoyl sphingosine; D-erythro-Ceramide; Phytosphingosine ceramide; N-2'-Hydroxybehenoyl phytosphingosine; Skin-identical ceramide analog
EINECS	Contact for details

Quality Control

Our n-(2'-(S)-Hydroxybehenoyl)-D-Erythro-Sphingosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and high-purity research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.