Description

n-Palmitoyl-1-Desoxymethylsphinganine (M17:0/16:0) is a high-purity, synthetic sphingolipid analog, a critical building block for advanced biochemical and pharmaceutical research. This compound serves as a vital standard and precursor in the study of sphingolipid metabolism, cell signaling, and membrane biology. It is essential for researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic reagent sectors requiring precise lipid structures for their work.

Application

• Biochemical Research Standard: Used as a certified reference material (CRM) for the quantification and identification of sphingolipids in complex biological matrices via mass spectrometry (LC-MS/MS).
• Pharmaceutical Development: Acts as a key intermediate or starting material in the synthesis of novel therapeutic agents targeting sphingolipid-related pathways, such as those involved in cancer, inflammation, and neurodegenerative diseases.
• Lipidomics & Metabolomics: An indispensable tool for profiling lipid species, enabling the study of disease biomarkers and metabolic disorders.
• Cell Biology Studies: Employed to investigate the role of specific sphingolipids in cell membrane structure, apoptosis, and signal transduction mechanisms.
• Diagnostic Reagent Manufacturing: Incorporated into the production of calibrators and controls for clinical diagnostic assays measuring sphingolipid levels.
• Academic Research: Supports fundamental research in universities and institutes focused on lipid biochemistry and molecular biology.

Basic Information

Product Name	n-Palmitoyl-1-Desoxymethylsphinganine (M17:0/16:0)
CAS No.	1246298-42-9
Molecular Formula	C34H69NO2
Molecular Weight	523.93 g/mol
Synonyms	N-[(2S,3R)-1,3-Dihydroxyoctadecan-2-yl]hexadecanamide; D-erythro-C17-Sphinganine N-Palmitoyl Amide; M17:0/16:0 Ceramide (dihydro); 1-Desoxymethylsphinganine Palmitate; Dihydroceramide (17:0/16:0); N-Palmitoyl-D-erythro-sphinganine; (2S,3R)-2-Hexadecanamidooctadecane-1,3-diol
EINECS	Contact for details

Quality Control

Every batch of n-Palmitoyl-1-Desoxymethylsphinganine (M17:0/16:0) is manufactured and analyzed under strict quality management systems. Our products undergo rigorous identity, purity, and stability testing using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to guarantee traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.