Description

n-Lauroyl-1-Desoxymethylsphinganine (M17:0/12:0) is a high-purity, synthetic sphingolipid analog, specifically an N-acylated sphinganine derivative. This compound serves as a critical reference standard and research-grade biochemical for advancing studies in lipidomics, membrane biology, and cellular signaling pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require well-defined lipid molecules for analytical method development, biomarker discovery, and investigating the role of sphingolipids in health and disease.

Application

• Biomedical Research: Used as a key analytical standard in mass spectrometry-based lipidomics for the identification and quantification of complex sphingolipid species in biological samples.
• Drug Discovery & Development: Serves as a precursor or intermediate in the synthesis of novel therapeutic agents targeting sphingolipid metabolism pathways.
• Cell Biology Studies: Employed to study the structure, function, and dynamics of lipid rafts and cell membranes, as well as sphingolipid-mediated signal transduction.
• Diagnostic Assay Development: Acts as a calibrant or control material in the development of clinical diagnostic tests for metabolic disorders related to sphingolipid imbalances.
• Biochemical Reagent: Utilized in enzymatic assays to study the activity of ceramide synthases and other enzymes involved in sphingolipid biosynthesis.
• Cosmeceutical Research: Investigated for potential applications in advanced skincare formulations targeting skin barrier function and cellular communication.

Basic Information

Product Name	n-Lauroyl-1-Desoxymethylsphinganine (M17:0/12:0)
CAS No.	1246298-41-8
Molecular Formula	C30H61NO2
Molecular Weight	467.82 g/mol
Synonyms	N-Dodecanoylsphinganine; Lauroylsphinganine; M17:0/12:0 Sphinganine; D-erythro-Sphinganine, N-(1-oxododecyl)-; N-Lauroyl-D-erythro-sphinganine; N-(1-Oxododecyl)-D-erythro-sphinganine; Sphinganine, N-lauroyl-; C12-Cer(d18:0)
EINECS	Contact for details

Quality Control

Our n-Lauroyl-1-Desoxymethylsphinganine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to support regulatory requirements for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. The product is light-sensitive and easily oxidized. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (Mass Spec)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.