Description

n-Lauroyl-1-Deoxysphinganine (M18:0/12:0) is a specific, high-purity sphingolipid analog, a critical building block for advanced biochemical research and development. This compound is essential for studying cellular signaling pathways, membrane biophysics, and the role of sphingolipids in metabolic and neurological processes. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic companies focused on lipidomics, biomarker discovery, and novel therapeutic agent synthesis. Our supply is characterized by stringent quality control to ensure batch-to-batch consistency for reliable experimental results.

Application

• Biochemical Research Standard: Used as a reference standard in mass spectrometry and chromatography for lipidomic profiling and quantification.
• Cell Biology Studies: Investigates the biological functions of deoxysphingolipids in cell proliferation, apoptosis, and signal transduction.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the development of therapies targeting metabolic disorders.
• Diagnostic Reagent Formulation: Incorporated into assay kits for the detection and study of sphingolipid-related diseases, such as hereditary sensory neuropathy type 1 (HSAN1).
• Membrane Biophysics: Employed in model membrane systems to study lipid-lipid and lipid-protein interactions.
• Academic Research: Fundamental tool for universities and research institutes exploring sphingolipid metabolism and its implications in health and disease.

Basic Information

Product Name	n-Lauroyl-1-Deoxysphinganine (M18:0/12:0)
CAS No.	1246298-40-7
Molecular Formula	C30H61NO2
Molecular Weight	467.82 g/mol
Synonyms	1-Deoxysphinganine C12:0; Lauroyl-deoxysphinganine; N-[(2S,3R)-2-Amino-3-hydroxyoctadecyl]dodecanamide; M18:0/12:0 Ceramide analog; Deoxysphingolipid base C12; 2-Amino-3-hydroxy-18-methyleicosanoyl-dodecanamide; Dihydrosphingosine lauroyl amide
EINECS	Contact for details

Quality Control

Our n-Lauroyl-1-Deoxysphinganine is manufactured under strict quality management protocols. Each batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support research and development requiring high-purity, well-characterized lipid standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.