Description

Biotin-Furfurylamine CAS NO 1246056-42-7 is a high-purity, bifunctional chemical building block that combines the biotin (vitamin B7) moiety with a reactive furfurylamine group. This molecular design is critical for creating targeted bioconjugates and probes used in advanced life science research and diagnostics. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent sectors for applications requiring specific molecular recognition and labeling.

Application

• Bioconjugation Reagent: For site-specific labeling of proteins, antibodies, and other biomolecules via the reactive amine group.
• Diagnostic Probe Synthesis: A key intermediate in manufacturing diagnostic kits, particularly for ELISA and lateral flow assays, leveraging biotin-streptavidin affinity.
• Chemical Biology Research: Used to create biotinylated small molecules, peptides, and oligonucleotides for target identification and pull-down assays.
• Drug Delivery Systems: Employed in the development of targeted drug delivery platforms where biotin facilitates receptor-mediated uptake.
• Surface Functionalization: Used to modify nanoparticles, biosensors, and microarray surfaces to create capture surfaces for biomolecules.
• Affinity Chromatography Ligand: Serves as a precursor for immobilizing ligands on solid supports for purification processes.

Basic Information

Product Name	Biotin-Furfurylamine
CAS No.	1246056-42-7
Molecular Formula	C16H25N3O3S
Molecular Weight	339.45 g/mol
Synonyms	Biotin-PEG1-Furfurylamine; 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(furan-2-ylmethyl)pentanamide; N-(Furfuryl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide; Biotin-FA; Biotinylated Furfurylamine; Vitamin B7-Furfurylamine Conjugate
EINECS	Contact for details

Quality Control

Our Biotin-Furfurylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture, to ensure it meets the stringent requirements for research and diagnostic applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.