Description

Fluorouracil(R) CAS NO 1235374-79-4 is a high-purity, fluorinated pyrimidine analog of significant importance in advanced pharmaceutical research and development. This compound serves as a critical building block and reference standard for the synthesis and quality control of novel anticancer agents and other therapeutic molecules. It is essential for research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in oncology drug discovery, metabolic studies, and analytical method development. Our supply ensures consistent quality and reliable availability for your most demanding projects.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the manufacture of advanced chemotherapeutic agents and targeted cancer therapies.
• Active Pharmaceutical Ingredient (API) Development: Used in research for formulating new dosage forms and drug delivery systems.
• Biochemical Research: Employed as a tool compound in studies of thymidylate synthase inhibition, nucleic acid metabolism, and cell proliferation pathways.
• Analytical Reference Standard: Serves as a high-purity standard for quality control (QC) and quality assurance (QA) in HPLC, LC-MS, and NMR analyses.
• Oncology Research: Utilized in in vitro and in vivo studies to investigate mechanisms of action, efficacy, and resistance profiles.
• Process Chemistry: Integral component in scaling up synthetic routes under current Good Manufacturing Practices (cGMP) for clinical trial material production.

Basic Information

Product Name	Fluorouracil(R) CAS NO 1235374-79-4
CAS No.	1235374-79-4
Molecular Formula	C4H3FN2O2
Molecular Weight	130.08 g/mol
Synonyms	5-Fluorouracil; 5-FU; 5-Fluoro-2,4(1H,3H)-pyrimidinedione; Adrucil; Carac; Efudex; Fluoroplex; Fluroblastin; 5-Fluoro-1H-pyrimidine-2,4-dione; NSC-19893; Arumel
EINECS	Contact for details

Quality Control

Every batch of Fluorouracil(R) is manufactured and tested to meet stringent quality standards suitable for research and pharmaceutical applications. Our quality assurance protocol includes comprehensive analytical testing to verify identity, purity, and potency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting results for key parameters such as assay, related substances, and residual solvents. We support compliance with relevant pharmacopeial guidelines (e.g., USP, EP) and can provide material for GMP-regulated processes upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.