Description

(1,3-Diethyl-2,5-Dioxo-Imidazolidin-4-Yl)-Acetic Acid 2,5-Dioxo-Pyrrolidin-1-Yl Ester is a specialized heterocyclic building block and active ester intermediate of significant interest in advanced organic synthesis. Its core value lies in its dual functionality, serving as a versatile coupling agent for the introduction of the (1,3-diethyl-2,5-dioxo-imidazolidin-4-yl)-acetic acid moiety under mild conditions. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in peptide mimetics and prodrug development. Its design facilitates efficient amide bond formation, making it a critical reagent for medicinal chemists.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing hydantoin or succinimide derivatives.
• Peptide Mimetic & Prodrug Synthesis: Used as an activated ester for coupling amino acids or other amines to create peptide-like structures or cleavable prodrug conjugates.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, or plant growth regulators with specific biological activity.
• Bioconjugation Chemistry: Employed to label biomolecules (e.g., proteins, antibodies) with reporter groups or linkers for diagnostic and therapeutic applications.
• Polymer & Material Science: Monomer or cross-linking agent for creating functional polymers with tailored properties, such as hydrogels or drug delivery systems.
• Chemical Biology Probes: Synthesis of activity-based probes or affinity labels for studying enzyme function and protein interactions.

Basic Information

Product Name	(1,3-Diethyl-2,5-Dioxo-Imidazolidin-4-Yl)-Acetic Acid 2,5-Dioxo-Pyrrolidin-1-Yl Ester
CAS No.	1222693-69-7
Molecular Formula	C13H17N3O6
Molecular Weight	311.29 g/mol
Synonyms	1-(2,5-Dioxopyrrolidin-1-yl) 2-[(4,5-diethyl-2,5-dioxo-1-imidazolidinyl)]acetate; N-Succinimidyl (1,3-diethyl-2,5-dioxo-4-imidazolidinyl)acetate; 2-(1,3-Diethyl-2,5-dioxoimidazolidin-4-yl)acetic acid N-hydroxysuccinimide ester; 4-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-4-oxo-2-(1,3-diethyl-2,5-dioxo-4-imidazolidinyl)butanoic acid; (1,3-Diethyl-2,5-dioxo-4-imidazolidinyl)acetic acid N-succinimidyl ester; Succinimidyl (1,3-diethyl-2,5-dioxo-4-imidazolidinyl)acetate; Active Ester of (1,3-Diethylhydantoin-4-yl)acetic Acid
EINECS	Contact for details

Quality Control

Our (1,3-Diethyl-2,5-Dioxo-Imidazolidin-4-Yl)-Acetic Acid 2,5-Dioxo-Pyrrolidin-1-Yl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent hydrolysis of the active ester. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.