Description

1-Desoxymethylsphinganine (M17:0) is a high-purity sphingoid base, a key intermediate and reference standard in lipidomics and sphingolipid research. This compound is critical for studying cellular signaling pathways, membrane biology, and metabolic disorders related to sphingolipid metabolism. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require precise and reliable lipid standards for analytical method development, biomarker discovery, and quality control.

Application

• Biomarker Research & Discovery: Used as a quantitative internal standard in mass spectrometry (LC-MS/MS, GC-MS) for the accurate measurement of endogenous sphingolipids in biological samples.
• Pharmaceutical R&D: Serves as a critical reference material and synthetic precursor in the development of novel therapeutics targeting sphingolipid-related pathways in cancer, inflammation, and neurodegenerative diseases.
• Diagnostic Assay Development: Employed in the calibration and validation of clinical diagnostic kits designed to detect and quantify sphingolipid imbalances.
• Academic & Institutional Research: A fundamental tool for investigating the role of sphingoid bases in cell proliferation, apoptosis, and stress responses.
• Quality Control & Metrology: Acts as a certified reference material (CRM) to ensure the accuracy and traceability of analytical results in contract research organizations (CROs) and testing laboratories.

Basic Information

Product Name	1-Desoxymethylsphinganine (M17:0)
CAS No.	1219484-98-6
Molecular Formula	C17H37NO2
Molecular Weight	287.49 g/mol
Synonyms	Dihydrosphingosine (d17:0); (2S,3R)-2-Amino-3-hydroxyheptadecane; Erythro-sphinganine (C17); M17:0 Sphingoid Base; Heptadecasphinganine; D-erythro-Dihydrosphingosine (C17); 2-Amino-1,3-heptadecanediol; Sphinganine (17:0)
EINECS	Contact for details

Quality Control

Our 1-Desoxymethylsphinganine (M17:0) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC-MS, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with research and cGMP guidelines for reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.