Description

2-Carboxyethyl Methanethiosulfonate, Choline Ester Chloride Salt is a specialized, high-purity biochemical reagent designed for advanced research and synthesis. This compound is valued for its role as a versatile, membrane-permeable thiol-modifying agent, enabling precise protein and peptide studies. It is primarily utilized by researchers and process chemists in the pharmaceutical, biotechnology, and life sciences sectors for applications including bioconjugation, enzyme inhibition, and the development of targeted therapeutics.

Application

• Bioconjugation and Protein Labeling: Used as a thiol-reactive crosslinker for site-specific modification of proteins, antibodies, and peptides.
• Enzyme Activity Studies: Serves as a tool compound for investigating enzyme mechanisms, particularly those involving cysteine residues.
• Pharmaceutical Intermediate: Acts as a key building block in the synthesis of novel drug candidates and prodrugs.
• Proteomics Research: Employed in mass spectrometry-based workflows for labeling and identifying thiol-containing biomolecules.
• Chemical Biology Probes: Utilized to develop activity-based probes for studying cellular processes and target engagement.
• Material Surface Functionalization: Applied in modifying surfaces for biosensor development and diagnostic device fabrication.

Basic Information

Product Name	2-Carboxyethyl Methanethiosulfonate, Choline Ester Chloride Salt
CAS No.	1219378-82-1
Molecular Formula	C9H20ClNO5S2
Molecular Weight	321.84 g/mol
Synonyms	MTSES-Choline Ester Chloride; (2-Carboxyethyl) Methanethiosulfonate Choline Ester Salt; 2-(Methanethiosulfonato)ethyl Hydrogen Succinate Choline Chloride; Choline (2-Carboxyethyl) Methanethiosulfonate Chloride; MTSEA-Choline Derivative; Thiol-Reactive Choline Ester; Bioconjugation Reagent 1219378-82-1; S-(2-Carboxyethyl) Methanethiosulfonate Choline Salt
EINECS	Contact for details

Quality Control

Every batch of 2-Carboxyethyl Methanethiosulfonate, Choline Ester Chloride Salt is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA), detailing results for assay, purity, and related substances, is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.