Description

Arachidonic Acid Alkyne is a specialized, chemically modified derivative of the essential ω-6 fatty acid, arachidonic acid, featuring an alkyne functional group. This modification is critical for advanced biochemical research and development, enabling precise labeling and tracking via click chemistry reactions. It is primarily utilized by researchers and developers in the life sciences sector, particularly in lipidomics, drug discovery, and the synthesis of novel bioactive probes and conjugates. The compound, identified by CAS No. 1219038-32-0, is designed for applications requiring high specificity and reactivity.

Application

• Bioconjugation and Probe Synthesis: Serves as a key building block for creating fluorescent, biotinylated, or other tagged lipid probes via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
• Lipidomics and Metabolic Tracing: Enables the study of arachidonic acid metabolism, incorporation into cellular membranes, and downstream eicosanoid signaling pathways through stable isotopic or fluorescent labeling.
• Drug Discovery & Target Identification: Used in activity-based protein profiling (ABPP) to identify and validate enzymes involved in lipid processing and inflammatory pathways.
• Material Science & Polymer Chemistry: Acts as a functional monomer for synthesizing specialized polymers with lipid-like properties for biomedical applications.
• Biomarker Development: Facilitates the creation of diagnostic tools and assays to detect and quantify specific lipid-derived metabolites.

Basic Information

Product Name	Arachidonic Acid Alkyne
CAS No.	1219038-32-0
Molecular Formula	C23H36O2
Molecular Weight	344.5 g/mol
Synonyms	(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraynoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid Alkyne Derivative; AA-Alkyne; 20:4 δ5,8,11,14 Alkyne; Clickable Arachidonic Acid; ω-6 Fatty Acid Alkyne Probe
EINECS	Contact for details

Quality Control

Our Arachidonic Acid Alkyne is produced under stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and absence of critical impurities. We adhere to relevant quality management standards to support our global clientele in pharmaceutical and academic research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, keep desiccated to minimize moisture exposure. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in DMSO, DMF, ethanol, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.