Description

(3As,4S,6Ar)-n-(16-Amino-2-Oxo-7,10,13-Trioxa-3-Azahexadec-1-Yl)Hexahydro-n-Methyl-2-Oxo-1H-Thieno[3,4-D]Imidazole-4-Pentanamide is a sophisticated, high-purity synthetic intermediate featuring a complex heterocyclic structure with a polyether linker. This compound is of significant value for its role in the development of targeted bioconjugates and advanced pharmaceutical agents, particularly in the fields of oncology and diagnostic imaging. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel drug candidates and bioconjugates requiring precise chemical modification.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule therapeutics and targeted drug conjugates.
• Bioconjugation Linker: Used to attach active pharmaceutical ingredients (APIs), fluorophores, or chelating agents to antibodies, peptides, or other biomolecules for targeted delivery.
• Proteolysis-Targeting Chimera (PROTAC) Development: Serves as a component in the design of heterobifunctional molecules for targeted protein degradation.
• Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and biological pathways.
• Diagnostic Agent Synthesis: Utilized in the creation of contrast agents or radiopharmaceuticals for medical imaging applications.
• Peptidomimetic Chemistry: Acts as a constrained scaffold in the design of peptide mimics with enhanced stability and bioavailability.

Basic Information

Product Name	(3As,4S,6Ar)-n-(16-Amino-2-Oxo-7,10,13-Trioxa-3-Azahexadec-1-Yl)Hexahydro-n-Methyl-2-Oxo-1H-Thieno[3,4-D]Imidazole-4-Pentanamide
CAS No.	1217717-09-3
Molecular Formula	C24H39N5O7S
Molecular Weight	541.66 g/mol
Synonyms	Biotin-PEG4-amine TFA salt; Biotin-PEG4-NH2; Biotin-PEG4-Amine; Biotinamido-PEG4-amine; 5-[(3aS,4S,6aR)-2-Oxo-1-(PEG4-amine)hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid; N-(16-Amino-2-oxo-7,10,13-trioxa-3-azahexadec-1-yl)-N-methyl-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazole-4-pentanamide; Biotin-PEG4-Amine (TFA Salt); Biotin-PEG4-NH2 TFA
EINECS	Contact for details

Quality Control

Our (3As,4S,6Ar)-n-(16-Amino-2-Oxo-7,10,13-Trioxa-3-Azahexadec-1-Yl)Hexahydro-n-Methyl-2-Oxo-1H-Thieno[3,4-D]Imidazole-4-Pentanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.