Description

Fmoc-(R)-3-Amino-3-(2-Furyl)-Propionic Acid is a high-purity, non-natural amino acid derivative featuring an Fmoc-protected amine group and a furan side chain. This compound is a critical chiral building block for the solid-phase synthesis of complex peptides and peptidomimetics, enabling the introduction of unique structural motifs. It is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel therapeutic agents and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediates: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in Fmoc-based solid-phase peptide synthesis (SPPS) to incorporate a furyl-functionalized amino acid residue into peptide chains.
• Peptidomimetic Design: Facilitates the creation of peptide-like molecules with enhanced metabolic stability and bioavailability for drug discovery.
• Chemical Biology Probes: Employed in the synthesis of labeled peptides and probes for studying protein-protein interactions and enzyme mechanisms.
• Combinatorial Chemistry: A valuable building block for generating diverse chemical libraries for high-throughput screening.
• Academic & Industrial R&D: Supports fundamental research in organic chemistry, medicinal chemistry, and biochemistry.

Basic Information

Product Name	Fmoc-(R)-3-Amino-3-(2-Furyl)-Propionic Acid
CAS No.	1217662-55-9
Molecular Formula	C22H19NO5
Molecular Weight	377.39 g/mol
Synonyms	Fmoc-(R)-3-Amino-3-(2-furyl)propanoic Acid; (R)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(furan-2-yl)propanoic Acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-furyl)-D-alanine; Fmoc-D-3-(2-Furyl)alanine; Fmoc-3-(2-Furyl)-D-alanine; N-Fmoc-3-(2-furyl)-D-alanine; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(furan-2-yl)propanoic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical applications. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, chiral purity, and chemical purity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.