Description

Nortilidine-D3 Hydrochloride is a deuterium-labeled isotopologue of the pharmaceutical compound Nortilidine, specifically designed for use as an internal standard in analytical chemistry. This high-purity reference material is critical for ensuring the accuracy and reliability of quantitative analyses, particularly in pharmacokinetic and metabolism studies. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, forensic, and clinical diagnostics sectors who require precise measurement of the parent compound.

Application

• Primary use as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the quantification of Nortilidine.
• Metabolite profiling and drug metabolism studies (DMPK) in pharmaceutical research and development.
• Bioanalytical method development and validation for clinical trial sample analysis.
• Forensic toxicology analysis for the accurate identification and quantification of Nortilidine in biological matrices.
• Quality control and assurance in pharmaceutical manufacturing processes.
• Use in stable isotope dilution assays to achieve high precision in analytical measurements.

Basic Information

Product Name	Nortilidine-D3 Hydrochloride
CAS No.	1217648-75-3
Molecular Formula	C20H22D3NO • HCl
Molecular Weight	Approx. 324.91 g/mol (Contact for exact details)
Synonyms	Nortilidine-d3 HCl; Nortilidine (phenyl-d3) Hydrochloride; 1-[2-[(2,3,4,5-Tetrahydro-1H-3-benzazepin-7-yl)oxy]ethyl]pyrrolidine-d3 Hydrochloride; Nortilidine Internal Standard; Deuterated Nortilidine HCl; Nortilidine-d3 for LC-MS; Nortilidine Isotopologue; Nortilidine-D3 (Hydrochloride Salt)
EINECS	Contact for details

Quality Control

Every batch of Nortilidine-D3 Hydrochloride is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data for identity, purity (by HPLC), isotopic enrichment, and residual solvents. Our quality protocols are designed to meet the stringent requirements of pharmaceutical reference standard applications, ensuring consistency and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.