Description

(R)-2,2-Dimethyl-1,3-Dioxolane-4-Acetamide is a high-purity chiral building block and intermediate of significant value in asymmetric synthesis. Its primary importance lies in its role as a precursor for the synthesis of complex, biologically active molecules, particularly in the pharmaceutical sector. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for the production of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly for antiviral, anticancer, and cardiovascular therapeutics.
• Asymmetric Synthesis: Used as a building block for constructing complex molecular architectures with defined stereochemistry in medicinal chemistry and total synthesis projects.
• Agrochemical Research: Serves as an intermediate in the development of chiral pesticides and herbicides where specific stereochemistry is crucial for activity and environmental safety.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high enantiomeric purity.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and catalysis research within university and corporate laboratories.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	(R)-2,2-Dimethyl-1,3-Dioxolane-4-Acetamide
CAS No.	1217619-56-1
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(R)-2,2-Dimethyl-1,3-dioxolane-4-acetamide; (4R)-2,2-Dimethyl-1,3-dioxolane-4-acetamide; (R)-1,3-Dioxolane-4-acetamide, 2,2-dimethyl-; D-Glyceraldehyde Acetonide Acetamide; (R)-Acetamide, 2,2-dimethyl-1,3-dioxolane-4-; (R)-Acetonide of D-Glyceraldehyde Acetamide; (R)-2,2-Dimethyl-[1,3]dioxolane-4-acetamide
EINECS	Contact for details

Quality Control

Our (R)-2,2-Dimethyl-1,3-Dioxolane-4-Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis (HPLC, GC), to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.