Description

Mono(2-Ethyl-5-Hydroxyhexyl) Phthalate Acyl Glucuronide is a specific metabolite of the plasticizer di(2-ethylhexyl) phthalate (DEHP), formed via the glucuronidation pathway. This compound is of critical importance for research and analytical laboratories focused on human biomonitoring and toxicological studies of phthalate exposure. It serves as a definitive biomarker for assessing DEHP metabolism, internal dose, and potential health impacts, making it essential for environmental health, occupational safety, and regulatory compliance sectors.

Application

• Biomonitoring Standard: Primary use as a certified reference material (CRM) or analytical standard for the quantitative measurement of DEHP exposure in human urine and serum.
• Toxicology Research: Critical for in vitro and in vivo studies investigating the pharmacokinetics, metabolism, and biological effects of DEHP and its metabolites.
• Clinical Studies: Enables precise correlation between phthalate exposure levels and health outcomes in epidemiological and clinical research.
• Regulatory & Safety Testing: Supports compliance testing for consumer product safety, occupational exposure limits, and environmental monitoring programs.
• Method Development & Validation: Used by analytical laboratories to develop, calibrate, and validate sensitive LC-MS/MS or GC-MS methods for phthalate metabolite detection.
• Quality Control/Assurance: Serves as a spike-in control for ensuring accuracy and precision in high-throughput biomonitoring laboratories.

Basic Information

Product Name	Mono(2-Ethyl-5-Hydroxyhexyl) Phthalate Acyl Glucuronide
CAS No.	1217463-85-8
Molecular Formula	C24H34O11
Molecular Weight	498.52 g/mol
Synonyms	MEHHG; 5-OH-MEHP Glucuronide; Mono(2-ethyl-5-hydroxyhexyl) phthalate β-D-glucuronide; 5-Hydroxy-mono(2-ethylhexyl) phthalate glucuronide; DEHP Metabolite Glucuronide; [1-[(2-Carboxybenzoyl)oxy]-5-ethylhexyl] β-D-Glucopyranosiduronic Acid; MEHHP-Gluc; CAS 1217463-85-8
EINECS	Contact for details

Quality Control

Our high-purity reference standards are manufactured and verified under strict quality management systems. Each batch is characterized using orthogonal analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) is provided, detailing batch-specific purity, chromatographic data, and storage recommendations. We support compliance with ISO 17034 and ISO/IEC 17025 requirements for reference material producers and testing laboratories.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation. The product is stable under these conditions for at least 24 months from the date of receipt.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference chromatogram
Identification (MS)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in methanol, acetonitrile, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.