Description

(S)-3-Amino-5-Hydroxyindane is a chiral indane derivative of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking high-purity, enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Employed as a building block in the synthesis of complex, enantiomerically pure molecules due to its defined stereochemistry.
• Agrochemical Research: Used in the development of new chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in stereoselective transformations.
• Academic and R&D Laboratories: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	(S)-3-Amino-5-Hydroxyindane
CAS No.	1213899-46-7
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	(3S)-3-Amino-5-hydroxy-2,3-dihydro-1H-indene; (S)-3-Amino-5-hydroxyindane; 5-Hydroxy-(S)-3-aminoindane; (S)-5-Hydroxy-3-aminoindane; 1H-Inden-5-ol, 3-amino-2,3-dihydro-, (3S)-; (3S)-3-Amino-2,3-dihydro-1H-inden-5-ol
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-5-Hydroxyindane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing identity, purity (typically ≥98%), enantiomeric excess (ee), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.