Description

(2S)-2-Amino-3-Cyclobutylpropan-1-Ol CAS NO 1213883-19-2 is a chiral, non-natural amino alcohol derivative featuring a cyclobutyl side chain, serving as a high-value building block in advanced organic synthesis. This compound is critical for medicinal chemistry research, enabling the development of novel, conformationally constrained bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for applications in peptide mimetics, chiral catalysts, and as a key intermediate in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease research.
• Peptidomimetics & Constrained Peptides: Used to introduce conformational rigidity into peptide backbones, enhancing metabolic stability and receptor selectivity.
• Chiral Ligand & Catalyst Synthesis: Serves as a precursor for developing novel asymmetric catalysts used in enantioselective transformations.
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme mechanisms and protein-protein interactions.
• Agrochemical Research: Employed in the discovery of new chiral active ingredients for crop protection.
• Academic & Industrial R&D: A versatile building block for exploratory synthetic chemistry and library development in high-throughput screening.

Basic Information

Product Name	(2S)-2-Amino-3-Cyclobutylpropan-1-Ol
CAS No.	1213883-19-2
Molecular Formula	C7H15NO
Molecular Weight	129.20 g/mol
Synonyms	(2S)-2-Amino-3-cyclobutyl-1-propanol; (S)-2-Amino-3-cyclobutylpropan-1-ol; L-2-Amino-3-cyclobutylpropan-1-ol; (S)-2-Amino-3-cyclobutylpropyl alcohol; 2-Amino-3-cyclobutyl-1-propanol, (2S)-; 1213883-19-2; (S)-3-Cyclobutylalaninol; (2S)-3-Cyclobutylalaninol
EINECS	Contact for details

Quality Control

Our (2S)-2-Amino-3-Cyclobutylpropan-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and chiral integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.