Description

N3-Peg9-Ch2Ch2Nh2 is a heterobifunctional polyethylene glycol (PEG) linker featuring an azide (N3) group and a primary amine (NH2) group, separated by a flexible PEG9 spacer. This compound matters as a critical reagent in bioconjugation and click chemistry, enabling the precise, high-yield coupling of biomolecules, polymers, and surfaces under mild, aqueous conditions. It is essential for researchers and manufacturers in pharmaceuticals, diagnostics, and advanced materials development who require reliable, water-soluble crosslinkers for creating novel conjugates, drug delivery systems, and functionalized nanomaterials.

Application

• Bioconjugation and Antibody-Drug Conjugate (ADC) Development: Site-specific coupling of cytotoxic drugs, fluorophores, or proteins to antibodies or other targeting molecules via amine-reactive chemistry and copper-free click reactions.
• Polymer and Biomaterial Functionalization: Introducing amine or azide handles onto polymer backbones, hydrogels, or nanoparticle surfaces to create reactive platforms for further modification.
• Peptide and Protein Modification: PEGylation of peptides or proteins at specific sites to enhance solubility, stability, and pharmacokinetic profiles.
• Diagnostic Assay Development: Conjugation of detection probes (enzymes, dyes) to antibodies or oligonucleotides for ELISA, lateral flow assays, or in situ hybridization.
• Surface Immobilization and Microarray Fabrication: Creating functionalized surfaces on chips, slides, or beads for capturing biomolecules in biosensor and high-throughput screening applications.
• Lipid and Vesicle Labeling: Incorporation into liposomes or lipid nanoparticles (LNPs) for targeted delivery and tracking.
• Synthesis of Branched or Multi-Arm PEG Derivatives: Serving as a versatile building block for constructing complex, multi-functional PEG architectures.

Basic Information

Item	Details
Product Name	N3-Peg9-Ch2Ch2Nh2
CAS No.	1207714-69-9
Molecular Formula	C23H48N6O10
Molecular Weight	568.66 g/mol
Synonyms	Azide-PEG9-amine; N3-PEG9-NH2; 2-[2-[2-[2-[2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethylamine; Amine-PEG9-azide; Heterobifunctional PEG9 linker, Azide-Amine; 1-Azido-3,6,9,12,15,18,21,24,27-nonaoxaoctacosan-28-amine; PEG9 spacer, N3/NH2
EINECS	Contact for details

Quality Control

Our N3-Peg9-Ch2Ch2Nh2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and Mass Spectrometry, to ensure it meets the high standards required for research and biopharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a dry environment before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or oil
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Functional Group Assay (Azide)	≥ 90% of theoretical
Functional Group Assay (Amine)	≥ 90% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.