Description

n-Biotinyl-Nh-(Peg)2-Co2H·Ndipea is a specialized bioconjugation reagent featuring a biotin moiety linked to a carboxylic acid functional group via a flexible, hydrophilic polyethylene glycol (PEG) spacer. This molecular architecture is critical for creating stable, high-affinity linkages in complex biochemical assays and diagnostic platforms. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic industries for applications requiring precise molecular tagging and immobilization, such as affinity purification, targeted drug delivery systems, and advanced biosensor development.

Application

• Affinity Chromatography Ligand Synthesis: Conjugation to resins or surfaces for the selective capture and purification of streptavidin/avidin-tagged proteins or other biomolecules.
• Diagnostic Assay Development: Labeling of antibodies, antigens, or oligonucleotides for use in ELISA, lateral flow tests, and other immunoassay formats.
• Targeted Drug Delivery Conjugation: Functionalization of nanoparticles, liposomes, or antibody-drug conjugates (ADCs) to enable biotin-streptavidin mediated targeting.
• Biosensor and Microarray Fabrication: Immobilization of probe molecules onto sensor chips or slides to create sensitive and specific detection platforms.
• Cell Surface Labeling and Imaging: Tagging of cell surface receptors or other proteins for visualization and tracking in fluorescence microscopy or flow cytometry.
• Protein and Peptide Modification: Site-specific biotinylation of proteins or peptides to study protein-protein interactions via pull-down assays.

Basic Information

Product Name	n-Biotinyl-Nh-(Peg)2-Co2H·Ndipea
CAS No.	1205744-09-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Biotin-PEG2-acid; Biotin-PEG2-COOH; Biotinamido-PEG2-propionic acid; Biotin-PEG2-propionic acid; N-Biotinyl-3,6-dioxaoctanedioic acid monoamide; Biotin-PEG2-C2-acid; Biotinylated PEG2 acid linker; 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-[2-(2-carboxyethoxy)ethoxy]ethyl]pentanamide
EINECS	Contact for details

Quality Control

Every batch of n-Biotinyl-Nh-(Peg)2-Co2H·Ndipea undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation (by NMR and/or MS), and other critical parameters is provided with each shipment to guarantee reliable performance in your sensitive bioconjugation workflows.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.