Description

Coptisine Sulfate CAS NO 1198398-71-8 is a high-purity sulfate salt of the natural isoquinoline alkaloid coptisine, derived from plants like *Coptis chinensis*. This compound is valued for its significant biological activity and serves as a critical reference standard and research-grade biochemical. It is primarily sought after by researchers and developers in the pharmaceutical, nutraceutical, and life science sectors for drug discovery and advanced biochemical studies.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of herbal extracts and finished products in quality control laboratories.
• Biochemical Research: Serves as a key intermediate or active ingredient in studies investigating anti-inflammatory, antimicrobial, and potential anticancer mechanisms.
• Natural Product Isolation & Synthesis: Acts as a pure benchmark for the isolation, purification, and semi-synthetic modification of related alkaloids.
• Analytical Method Development: Essential for developing and validating chromatographic methods (HPLC, LC-MS) for complex botanical matrices.
• Nutraceutical Formulation R&D: Employed in the research and development of standardized herbal supplements.
• Academic Research: Used in university and institutional labs for pharmacological and phytochemical studies.

Basic Information

Product Name	Coptisine Sulfate
CAS No.	1198398-71-8
Molecular Formula	C19H14NO4 · H2SO4
Molecular Weight	424.39 g/mol (for C19H14NO4 · H2SO4)
Synonyms	Coptisine sulfate salt; 8-Oxocoptisine sulfate; [1,3]Dioxolo[4,5-g]isoquinolin-7-ium, 5,6-dihydro-2,10,11-trihydroxy-3,9-dimethoxy-, sulfate (1:1); Coptisine sulphate; Coptis alkaloid sulfate
EINECS	Contact for details

Quality Control

Our Coptisine Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.