Description

11-Hydroxygelsenicine is a specialized, high-purity alkaloid derivative of significant interest in advanced research and development. This compound matters as a critical reference standard and building block for pharmacological studies, particularly in the investigation of natural product derivatives and their biological activities. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing novel therapeutic agents or analytical methods.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical methods (HPLC, LC-MS) for quality control and compound identification in drug discovery pipelines.
• Medicinal Chemistry Research: Serves as a key intermediate or precursor for the synthesis of novel analogs to study structure-activity relationships (SAR).
• Biochemical Assay Development: Employed in in vitro and in vivo studies to probe specific biological pathways and mechanisms of action.
• Natural Product Isolation & Analysis: Acts as a critical marker compound for the authentication and standardization of extracts from Gelsemium species and related botanicals.
• Academic & Institutional Research: Utilized in university and government labs for fundamental research in alkaloid chemistry, toxicology, and pharmacology.
• Fine Chemical Synthesis: Provides a sophisticated chiral scaffold for the multi-step synthesis of complex molecules in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Item	Detail
Product Name	11-Hydroxygelsenicine
CAS No.	1195760-68-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	11-Hydroxygelsemicine; 11-Hydroxy-gelsenicine; (19Z)-11-Hydroxygelsenicine; Gelsenicine, 11-hydroxy-; 11-Hydroxy-19Z-gelsenicine; 11-OH-Gelsenicine
EINECS	Contact for details

Quality Control

Our 11-Hydroxygelsenicine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC purity analysis, mass spectrometry (MS) for identity confirmation, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. For long-term storage, consider keeping the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.