Description

Amino-Peg9-Acid CAS NO 1191079-83-0 is a high-purity, heterobifunctional polyethylene glycol (PEG) derivative featuring a primary amine group at one terminus and a carboxylic acid group at the other, separated by a nonaethylene glycol spacer. This unique structure makes it an essential building block for creating stable, hydrophilic, and biocompatible crosslinks in advanced bioconjugation and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise, water-soluble linkers for modifying peptides, proteins, antibodies, and surfaces.

Application

• Bioconjugation and Linker Chemistry: A critical reagent for creating stable amide bonds, used to conjugate drugs, dyes, or other functional molecules to peptides, proteins, and antibodies, enhancing solubility and reducing immunogenicity.
• ADC (Antibody-Drug Conjugate) Development: Serves as a functionalized PEG spacer in the synthesis of ADCs, helping to optimize the drug-to-antibody ratio (DAR) and improve pharmacokinetic profiles.
• Surface Functionalization: Used to modify nanoparticles, quantum dots, and diagnostic assay surfaces with amine or carboxyl groups to introduce specific biorecognition elements.
• Hydrogel and Biomaterial Synthesis: Acts as a crosslinking agent or functional monomer in the creation of hydrophilic, biocompatible hydrogels for drug delivery and tissue engineering applications.
• Peptide Synthesis and Modification: Employed as a soluble spacer to introduce PEG chains (PEGylation) onto synthetic peptides, improving their stability and circulatory half-life.
• Diagnostic Reagent Preparation: Utilized in the development of enzyme conjugates and labeled probes for immunoassays (ELISA, lateral flow) and other diagnostic platforms.

Basic Information

Product Name	Amino-Peg9-Acid
CAS No.	1191079-83-0
Molecular Formula	C20H41NO11
Molecular Weight	471.54 g/mol
Synonyms	15-Amino-4,7,10,13-tetraoxapentadecanoic Acid; 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-oic acid, 27-amino-; NH2-PEG9-COOH; α-Amino-ω-carboxy-nonaethylene glycol; Amine-PEG9-acid; 27-Amino-2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-oic acid; 15-Amino-4,7,10,13-tetraoxa-pentadecanoic acid
EINECS	Contact for details

Quality Control

Our Amino-Peg9-Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and support your regulatory documentation needs for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, consider sealing under argon or nitrogen. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Amine Value (Titration)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.