Description

Omeprazole-D3 Sulfone CAS NO 1189891-71-1 is a deuterated isotopologue of the omeprazole sulfone metabolite, a key reference standard in analytical chemistry. This high-purity compound is essential for ensuring the accuracy and reliability of mass spectrometry-based bioanalytical methods. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and quality control departments for conducting precise pharmacokinetic, metabolic, and stability studies.

Application

• Used as an internal standard for the quantitative analysis of omeprazole and its metabolites in biological matrices via LC-MS/MS.
• Critical for drug metabolism and pharmacokinetics (DMPK) studies to understand the metabolic pathways of proton pump inhibitors.
• Facilitates bioequivalence and clinical trial research requiring high-sensitivity detection of drug compounds.
• Employed in the development and validation of regulatory-compliant analytical methods for pharmaceutical quality control.
• Serves as a reference material in forensic and anti-doping analysis for substance identification and confirmation.
• Essential for stable isotope dilution assays to achieve superior accuracy and precision in quantitative measurements.

Basic Information

Product Name	Omeprazole-D3 Sulfone
CAS No.	1189891-71-1
Molecular Formula	C17H16D3N3O4S
Molecular Weight	362.42 g/mol
Synonyms	5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl-d3)methyl]sulfinyl]-1H-benzimidazole Sulfone; Omeprazole Sulfone-d3; 5-Methoxy-2-{[(4-methoxy-3,5-dimethyl-2-pyridinyl-d3)methyl]sulfonyl}-1H-benzimidazole; Deuterated Omeprazole Sulfone; Omeprazole D3 Sulfone; Omeprazole Sulfone (D3); [D3]-Omeprazole Sulfone
EINECS	Contact for details

Quality Control

Every batch of Omeprazole-D3 Sulfone is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and isotopic enrichment meet the highest standards for reference materials. Our quality commitment includes traceable documentation and stability-indicating methods. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), isotopic purity (by MS), and all relevant specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 99.0% D3
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.